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The Clinical Laboratory Improvement Amendments of 1988 (CLIA) regulations include federal standards applicable to all U.S. facilities or sites that test human specimens for health assessment or to diagnose, prevent, or treat disease. CDC, in partnership with CMS and FDA, supports the CLIA program and clinical laboratory quality.

CDC’s responsibilities for the national CLIA program include:

  • Providing analysis, research, and technical assistance
  • Developing technical standards and laboratory practice guidelines, including standards and guidelines for cytology
  • Conducting laboratory quality improvement studies
  • Monitoring proficiency testing practices
  • Developing and distributing professional information and educational resources
  • Managing the Clinical Laboratory Improvement Advisory Committee (CLIAC)
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CLIA News and Announcements

  • The Centers for Disease Control and Prevention (CDC), Center for Surveillance, Epidemiology, and Laboratory Services (CSELS), Division of Laboratory Systems (DLS) would like to announce the publication of the following 2 Funding Opportunity Announcements (FOAs) in

    CDC-RFA-OE16-1602 Use of a Medical Data Warehouse in a Laboratory Quality Improvement Initiative that Links to Patient and System Outcomes.
    The purpose of this project is to support a collaborative opportunity to develop, implement, and evaluate a process to assess the usefulness of data contained within a medical data warehouse to document and address quality gaps in the pre-, intra-, and/or post-analytic phases of clinical laboratory medicine that can be linked to patient and/or system outcomes.
    Please go to, for more information and an application.  Application are due April 22, 2016.

     CDC-RFA-OE16-1603 Improving Waived Testing Performance and Outcomes through Partnerships.
    The purpose of the project is to support and expand the efforts of the laboratory and stakeholder organizations to instill quality practices, including applicable minimum Clinical Laboratory Improvement Amendments of 1988 (CLIA) requirements and good laboratory practice recommendations, in Certificate of Waiver (CW) sites nationwide to improve patient safety and health outcomes.
    Please go to, for more information and an application. Applications are due April 22, 2016.

     — 03/14/2016

News and Announcements Archive