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Genetic Testing Reference Materials Coordination Program (GeT-RM) - Home


GeT-RM Logo The goal of the Genetic Testing Reference Materials Coordination Program (GeT-RM) is to coordinate a self-sustaining community process to improve the availability of appropriate and characterized reference materials for:
  • Quality control (QC)
  • Proficiency testing (PT)
  • Test development & validation
  • Research
The purpose of this program is:
  • To help the genetic testing community obtain appropriate and characterized reference materials
  • To facilitate and coordinate information exchange between users and providers of QC and reference materials
  • To coordinate efforts for contribution, development, characterization and distribution of reference materials for genetic testing


List of GeT-RM Publications


We provide information about cell lines, DNA, and other kinds of materials that could be used as reference materials for molecular genetic testing. Some of these materials have been characterized by the GeT-RM program and can be divided into three categories:

Genetic Inherited Disease & Pharmacogenetics

This section includes information about cell lines, DNA, and other samples that can be used as reference materials for various inherited diseases (including cystic fibrosis, fragile X, Huntington disease, and Ashkenazi Jewish-related diseases), pharmacogenetic loci, and biochemical genetics. The GeT-RM program has confirmed the genotype of many of the genomic DNA samples through testing in multiple clinical genetic laboratories.
Materials Currently Available
Reference Articles

Molecular Oncology

This section includes information about commercially available cell lines, DNA, and other kinds of materials that could be used as reference materials for various types of cancers, including leukemia/lymphoma and solid tumors.
Materials Currently Available
Reference Articles

Infectious Disease

This section includes information about commercially available cell lines, DNA, and other kinds of materials that could be used as reference materials for various infectious disease pathogens including viruses, bacteria, and protozoa.
Materials Currently Available
Reference Articles


More general information pertaining to our program can also be found under the following links:
"Higher Order" Reference Materials (SRMs/CRMs/FDA/CE):
This link provides information about reference materials that are classified as either standardized reference materials (SRM), certified reference materials (CRM), FDA-cleared reference materials, or CE-marked reference materials.
Reference Materials Sources:
This link provides information about the various sources of available reference materials.
Guidance and Oversight:
This link provides insight into various regulatory guidelines and standards regarding reference materials.
Collaborator Acknowledgements:
This link provides information about individuals who have helped the GeT-RM to achieve its goals.

On the left hand navigation panel, the three categories as well as general reference material information can be efficiently accessed. Clicking on any category will allow you to view existing reference materials within that category or view reference articles related to that category.

GeT-RM Contact Information

Lisa Kalman, PhD
Program Coordinator
lkalman@cdc.gov


Disclaimer:The CDC is not responsible for the validity of mutations in cell lines or any other materials. Inclusion of commercially available materials or reagents on this website does not constitute an endorsement of such materials by the CDC and no endorsement shall be stated or inferred.
 
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