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Key Terms

Clinically compatible case

A clinical syndrome generally compatible with the disease, as described in the clinical description.

Confirmed case

A case that is classified as confirmed for reporting purposes.

Epidemiologically linked case

A case in which:

  • the patient has had contact with one or more persons who either have/had the disease or have been exposed to a point source of infection (i.e., a single source of infection, such as an event leading to a foodborne-disease outbreak, to which all confirmed case-patients were exposed)
  • transmission of the agent by the usual modes of transmission is plausible.  A case may be considered epidemiologically linked to a laboratory-confirmed case if at least one case in the chain of transmission is laboratory confirmed.

Laboratory-confirmed case

A case that is confirmed by one or more of the laboratory methods listed in the case definition under Laboratory Criteria for Diagnosis.  Although other laboratory methods can be used in clinical diagnosis, only those listed are accepted as laboratory confirmation for national reporting purposes.

Message Validation, Processing, and Provisioning System

The CDC MVPS is a software solution that will validate and process nationally notifiable disease data messages sent by jurisdictions and provision the data to the CDC programs.

The MVPS will provide several benefits to jurisdictions and CDC programs:

  • The MVPS will reduce the number of systems processing data at CDC and allow for streamlined message processing from jurisdictions to CDC.
  • The MVPS will reduce the number of systems processing data at CDC and allow for streamlined message processing from jurisdictions to CDC.
  • The MVPS aims to increase availability of data elements to CDC programs. Through the use of HL7 standards, the MVPS can increase the amount of data available to programs, thus increasing the granularity of data analysis. These HL7 formats include more data elements and more detailed data elements than formats such as NETSS or other flat files.
  • The MVPS will provide a Message Monitoring Dashboard that will allow jurisdictions to identify notifications that have been received by MVPS and perform near real-time reconciliation of message counts sent to and received by MVPS.

The MVPS is anticipated to be a component of the CDC Platform (CDCP), a broader concept that CDC has envisioned to expand public health shared services and enhance reporting and analytics at CDC for public health surveillance. The development of the CDCP is expected to occur over several years in several phases and will undergo further definition at a future date.

National Electronic Disease Surveillance System (NEDSS)

A key component of NNDSS is the National Electronic Disease Surveillance System. NEDSS provides data and information technology standards, support, and leadership to state, local, and territorial health departments. These health departments provide CDC with data on nationally notifiable diseases and conditions.

National Electronic Telecommunications System for Surveillance (NETSS)

Before implementing NEDSS, CDC developed and used the National Electronic Telecommunications System for Surveillance. NETSS is a computerized public health surveillance information system that provides CDC with weekly data regarding nationally notifiable diseases. NETSS continues to be used by jurisdictions that are transitioning to the more robust NEDSS. A bare-bones approach for providing basic data and information, NETSS file content has not been changed or updated substantially since NETSS launched in 1990.

National Notifiable Diseases Surveillance System (NNDSS)

The National Notifiable Diseases Surveillance System is a nationwide collaboration that enables all levels of public health (local, state, territorial, federal, and international) to share health information to monitor, control, and prevent the occurrence and spread of state-reportable and nationally notifiable infectious and some non-infectious diseases and conditions. NNDSS is a multifaceted program that includes the surveillance system for collection, analysis, and sharing of health data and also policies, laws, electronic messaging standards, people, partners, information systems, processes, and resources at the local, state, and national levels.

NEDSS Base System (NBS)

The National Electronic Disease Surveillance System Base System is a CDC-built application that provides jurisdictions with a NEDSS-compatible information system to transfer health, laboratory, and clinical data efficiently and securely over the Internet. NBS also provides public health authorities with a tool for processing, analyzing, and sharing data they receive.

Probable case

A case that is classified as probable for reporting purposes.

Supportive or presumptive laboratory results

Specified laboratory results that are consistent with the diagnosis, yet do not meet the criteria for laboratory confirmation.

Suspected case

A case that is classified as suspected for reporting purposes.