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Yellow Book

CDC Health Information for International Travel 2008

Chapter 5
Yellow Fever Vaccine Requirements and Information on Malaria Risk and Prophylaxis, by Country

Yellow Fever Vaccine Requirements and Information on Malaria Risk and Prophylaxis, by Country

CountryYellow FeverMalaria
Requirements1CDC recommendations2,4Area of riskChloroquine resistanceRecommended prophylaxis
AfghanistanIf traveling from an endemic zoneNoneRisk April-December in all areas at altitudes below 2,000m (<6,561ft)Confirmed

Atovaquone/ proguanil, doxycycline, or mefloquine

AlbaniaIf traveling from an endemic zone and >1 year of ageNoneNoneNot ApplicableNot Applicable
AlgeriaIf traveling from an endemic zone and >1 year of ageNoneRisk is limited to one small focus in Sahara region in Ihrir (Illizi Department). Risk is very limited; therefore, prophylaxis is not recommended.NoneNone
Samoa, American      
AndorraNot RequiredNoneNoneNot ApplicableNot Applicable
AngolaRequired upon arrival from all countriesFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Anguilla (U.K.)

If traveling from an endemic zone and >1 year of age

None

None

Not Applicable

Not Applicable

AntarcticaNot RequiredNoneNoneNot ApplicableNot Applicable
Antigua and Barbuda

If traveling from an endemic zone and >1 year of age

None

None

Not Applicable

Not Applicable

Argentina

Not Required

For all travelers >9 months of age going to the northern and northeastern forested areas, including Iguaçu Falls and all parts of Misiones Province, as well as all areas bordering Paraguay and Brazil. These areas include: all departments of Misiones and Formosa Provinces; Department of Bermejo in Chaco Province; Departments of Berón de Astrada, Capital, General Alvear, General Paz, Ituzaingó, Itatí, Paso de los Libres, San Cosme, San Miguel, San Martín and Santo Tomé in Corrientes Province; Departments of Valle Grande, Ledesma, Santa Bárbara and San Pedro in Jujuy Province; and Departments of General José de San Martín, Oran, Rivadavia and Anta in Salta Province (see Updated yellow fever risk map for Argentina). Updated April 17, 2008Rural areas of Salta and Jujuy province (along border with Bolivia) and Misiones and Corrientes province (along border with Paraguay).

None

Chloroquine

Armenia

Not Required

None

Risk limited to the Ararat Valley in the Ararat and Artashat region; greatest risk in Masis district.

None

Chloroquine
ArubaIf traveling from an endemic zone and >6 months of age3.NoneNoneNot ApplicableNot Applicable
Australia; Including Cocos (Keeling) Islands

All persons >1 year of age who, within 6 days of arrival in Australia, have been in or have passed through an endemic zone

None

None

Not Applicable

Not Applicable

Austria

Not Required

None

None

Not Applicable

Not Applicable

Azerbaijan

Not Required

None

Rural lowlands near Kura and Arax rivers in the provinces of Agcabadi, Barda, Beylaqan, Bilasuvar, Calilabad, Fuzuli, Imisli, Kurdamir, Nakhichivan, Sabirabad, Saatli and Zardab typically between July and October.

None

Chloroquine

Azores (Portugal)

If traveling from an endemic zone and >1 year of age

None

None

Not Applicable

Not Applicable

Bahamas, The

If traveling from an endemic zone and >1 year of age

None

Island of Great Exuma only. There is currently no known risk of malaria on other islands in The Bahamas.

None

Chloroquine

Bahrain

Not Required

None

None

Not Applicable

Not Applicable

Bangladesh

If traveling from an endemic zone. Any person (including infants)3 arriving by air or sea without a certificate within 6 days of departure from or transit through an infected area will be quarantined up to 6 days.

Required also for travelers arriving from or transiting:

Africa: Angola, Benin, Burkina Faso, Burundi, Cameroon, Central African Republic, Chad, Congo, Côte d’Ivoire, Democratic Republic of Congo, Equatorial Guinea, Ethiopia, Gabon, The Gambia, Ghana, Guinea, Guinea Bissau, Kenya, Liberia, Malawi, Mali, Mauritania, Niger, Nigeria, Rwanda, São Tomé and Principe, Senegal, Sierra Leone, Somalia, Sudan (south of 15° N), Tanzania, Togo, Uganda, and Zambia.

Americas: Belize, Bolivia, Brazil, Colombia, Costa Rica, Ecuador, French Guiana, Guatemala,
Guyana, Honduras, Nicaragua, Panama, Peru, Suriname, and Venezuela.

Caribbean: Trinidad and Tobago.

None

All, except no risk in city of Dhaka

Confirmed

Atovaquone/ proguanil, doxycycline, or mefloquine

BarbadosIf coming from an endemic zone and >1 of age

None

None

Not Applicable

Not Applicable

Belarus

Not Required

None

None

Not Applicable

Not Applicable

Belgium

Not Required

None

None

Not Applicable

Not Applicable

BelizeIf traveling from an endemic zone and >1 year of ageNoneAll, except no risk in Belize CityNoneChloroquine
BeninRequired upon arrival from all countries if traveler is > 1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Bermuda (U.K.)

Not Required

None

None

Not Applicable

Not Applicable

Bhutan

If traveling from an endemic zone

None

Risk in rural areas below 1,700 m (<5,577 ft) of the 5 southern belt districts of: Chirang, Samchi, Samdrup Jongkhar, Sarpang, and Shemgang

Confirmed

Atovaquone/ proguanil, doxycycline, or mefloquine

BoliviaRequired for all travelers >1 year of age. Medical waivers must be translated into Spanish and accompany the International Certificate of Vaccination or Prophylaxis (ICVP). Travelers who do not have a valid ICVP will still be allowed to enter Bolivia if they agree to sign an affidavit exempting the Bolivian state from any liability in the event the traveler gets sick with yellow fever within the Bolivian territory. This last option may cause delays at the point of entry.For all travelers >9 months of age traveling to areas east of the Andes Mountains (see Map 4-16). Does not include the cities of La Paz or Sucre.Risk in areas below 2,500 m (<8,202 ft) in the following departments:
Beni, Chuquisaca, Cochabamba, La Paz, Pando, Santa Cruz, and Tarija. No risk in city of La Paz.
ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Bosnia and Herzegovina

Not Required

None

None

Not Applicable

Not Applicable

Botswana

If traveling from an endemic zone and >1 year of age

None

Risk north of 22°S in the northern provinces of Central, Chobe, Ghanzi, Ngamiland, and including safaris to the Okavango Delta area. No risk in the city of Gaborone.

Confirmed

Atovaquone/ proguanil, doxycycline, or mefloquine

BrazilNot requiredFor all travelers ≥9 months of age going to the following areas at risk for yellow fever transmission, including the ENTIRE states of Acre, Amapá, Amazones, Distrito Federal (including the capital city of Brasília),  Goiás, Maranhão, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Pará, Rondônia, Roraima, Tocantins, and designated areas of the following states: northwest and west Bahia, central and west Paraná, southwest Piauí, northwest and west central Rio Grande do Sul, far west Santa Catarina, and north and west São Paulo. (See CDC Yellow Fever Risk Map for Brazil.) Vaccination is also recommended for travelers visiting Iguassu Falls. Vaccination is NOT recommended for travel to the following coastal cities: Rio de Janeiro, São Paulo, Salvador, Recife, and Fortaleza.States of Acre, Rondônia, Amapá, Amazonas, Roraima, and Tocantins. Parts of states of Maranhaõ (western part), Mato Grosso (northern part), and Pará (except Belem City). There is also transmission in urban areas, including large cities such as Porto Velho, Boa Vista, Macapa, Manaus, Santarem, and Maraba, where transmission occurs on the periphery of these cities.

Confirmed

Atovaquone/ proguanil, doxycycline, or mefloquine

British Indian Ocean Territory; Includes Diego Garcia (U.K.)

Not Required

None

None

Not Required

Not Required

Brunei

If traveling from an endemic zone and >1 year of age

None

None

Not Applicable

Not Applicable

Bulgaria

Not Required

None

None

Not Applicable

Not Applicable

Burkina FasoRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Burma (Myanmar)

If traveling from an endemic zone.

Required also for nationals and residents of Burma (Myanmar) departing for an endemic zone

None

Risk in rural areas throughout the country at altitudes below 1000 m (<3,281 ft). No risk in cities of Rangoon (Yangon) and Mandalay

Confirmed

Only atovaquone/ proguanil or doxycycline in the provinces of Shan, Kayah, Kachin, Kayin, and Tanintharyi. All other areas atovaquone/ proguanil, doxycycline, or mefloquine (see Map 4-9).
BurundiRequired upon arrival from all countriesFor all travelers >9 months of ageAll

Confirmed

Atovaquone/ proguanil, doxycycline, or mefloquine

CambodiaIf traveling from an endemic zone

None

Risk throughout the country, including risk in the temple complex at Angkor Wat. No risk in Phnom Penh and around Lake Tonle Sap.

Confirmed

Only atovaquone/ proguanil or doxycycline in the provinces of Preah Vihear, Siemreap, Oddar, Meanchey, Banteay Meanchey, Battambang, Pailin, Koh Kong, and Pursat bordering Thailand. All other areas atovaquone/ proguanil, doxycycline, or mefloquine. (see Map 4-9)

CameroonRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Canada

Not required

None

None

Not applicable

Not applicable

Canary Islands (Spain)

Not required

None

None

Not applicable

Not applicable

Cape Verde

If traveling from an endemic zone and >1 year of age.

None

Risk limited to Saõ Tiago Island.

Confirmed

Atovaquone/ proguanil, doxycycline, or mefloquine

Cayman Islands (U.K.)

Not required

None

None

Not applicable

Not applicable

Central African RepublicRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
ChadRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of age.AllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Chile

Not required

None

None

Not applicable

Not applicable

China

If traveling from an endemic zone

None

Travelers to cities and popular tourist areas, including Yangtze River cruises, are not at risk and do not need to take chemoprophylaxis. Rural areas only of the following provinces: Hainan, Yunnan, Fuijan, Guangdong, Guangxi, Guizhou, Sichuan, Tibet (in the Zangbo River valley only), Anhui, Hubei, Hunan, Jiangsu, Jiangxi, and Shandong. In provinces with risk, transmission exists in rural communities below 1,500 m only during warm weather: north of latitude 33°N, July-November; between latitude 25°N and 33°N, May-December. South of latitude 25°N, transmission occurs year-round.

Confirmed in the provinces of Hainin and Yunnan. Other provinces do not have chloroquine-resistant malaria.

Only atovaquone/ proguanil or doxycycline along China-Burma border in the western part of Yunnan province; Atovaquone/ proguanil, doxycycline or mefloquine in Hainan and the other parts of Yunnan province (see Map 4-9); Chloroquine in all other areas.

Christmas Island (Australia)All travelers >1 year of age, who within the past 6 days have traveled or passed through an endemic area, as listed by WHO.NoneNoneNot applicableNot applicable
Cocos (Keeling) Islands

All persons >1 year of age who, within 6 days of arrival in Australia, have been in or have passed through an endemic zone

None

None

Not Applicable

Not Applicable

ColombiaNot requiredFor all travelers >9 months of age. Travelers whose itinerary is limited to the cities of Bogotá, Cali, or Medellín are at lower risk and may consider foregoing vaccination.Risk in all rural areas at altitudes below 800 m (<2,624 ft). No risk in Bogotá and vicinity.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
ComorosNot requiredNoneAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
CongoRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Cook Islands (New Zeland)Not requiredNoneNoneNot applicableNot applicable
Costa Rica

If traveling from the endemic zones listed below:

Africa: Angola, Benin, Burkina Faso, Cameroon, Democratic Republic of Congo, Gabon, Gambia, Ghana, Guinea, Liberia, Nigeria, Sierra Leone, and Sudan.

Americas: Bolivia, Brazil, Colombia, Ecuador, French Guiana, Peru, and Venezuela.
(Updated September 24, 2007)

NoneRisk in Alajuela, Limón, Guanacaste, and Heredia provinces. No risk in Limón city (Puerto Limón).NoneChloroquine
Côte d'Ivoire (Ivory Coast)Required upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
CroatiaNot requiredNoneNoneNot applicableNot applicable
CubaNot requiredNoneNoneNot applicableNot applicable
CyprusNot requiredNoneNoneNot applicableNot applicable
Czech RepublicNot requiredNoneNoneNot applicableNot applicable
Democratic Republic of the CongoRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
DenmarkNot requiredNoneNoneNot applicableNot applicable
DjiboutiIf traveling from an endemic zone and >1 year of ageNoneAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
DominicaIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Dominican RepublicNot requiredNoneRural, with highest risk in provinces bordering Haiti. In addition, risk in all areas of La Altagracia Province, including resort areas.NoneChloroquine
Easter Island (Chile)Required for travelers coming from an endemic zoneNoneNoneNot applicableNot applicable
Ecuador, including the Galápagos Islands

If traveling from an endemic zone and >1 year of age

For all travelers >9 months of age who are traveling to the following provinces in the Amazon Basin: Morona-Santiago, Napo, Orellana, Pastaza, Sucumbíos, and Zamora-Chinchipe, and all other areas in the eastern part of the Andes Mountains, NOT including the cities of Quito and Guayaquil or the Galápagos Islands (see Updated yellow fever risk map for Ecuador). Updated May 5, 2008

Risk in all areas at altitudes below 1,500 m (<4,921 ft). No risk in the cities of Guayaquil and Quito, the central highland tourist areas, and the Galápagos Islands.

Confirmed

Atovaquone/ proguanil, doxycycline, or mefloquine

EgyptIf traveling from an endemic zone and >1 year of age. Air passengers in transit but coming from these countries or areas without a certificate will be detained in the precincts of the airport until they resume their journey. All travelers arriving from Sudan are required to have a vaccination certificate or a location certificate issued by a Sudanese official center, stating that they have not been in Sudan south of 15° N within the previous 6 days.

 

Required also for travelers arriving from or transiting:

Africa: Angola, Benin, Burkina Faso, Burundi, Cameroon, Central African Republic, Chad, Congo, Côte d’Ivoire, Democratic Republic of Congo, Equatorial Guinea, Ethiopia, Gabon, Gambia, Ghana, Guinea, Guinea Bissau, Kenya, Liberia, Mali, Niger, Nigeria, Rwanda, São Tomé and Principe, Senegal, Sierra Leone, Somalia, Sudan (south of 15° N), Tanzania, Togo, Uganda, and Zambia.

Americas: Belize, Bolivia, Brazil, Colombia, Costa Rica, Ecuador, French Guiana, Guyana, Panama, Peru, Suriname, and Venezuela.

Caribbean: Trinidad and Tobago.

NoneVery limited risk in El Faiyûm area only. No risk in tourist areas, including Nile River cruises. Risk is very limited; therefore, prophylaxis is not recommended.NoneNone
El SalvadorIf traveling from an endemic zone and >6 months of age3NoneRural areas of Santa Ana, Ahuachapán, and La Unión departments. No risk in the city of San Salvador.NoneChloroquine
Equatorial GuineaIf traveling from an endemic zoneFor all travelers >9 months of age.AllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
EritreaIf traveling from an endemic zoneNoneAll areas at altitudes below 2,200 m (<7,218 ft). No risk in Asmara.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
EstoniaNot requiredNoneNoneNot applicableNot applicable
EthiopiaIf traveling from an endemic zone and >1 year of ageFor all travelers >9 months of age.All areas at altitudes below 2,000 m (<6,561 ft). No risk in Addis Ababa.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Falkland Islands (U.K.)Not requiredNoneNoneNot applicableNot applicable
Faroe Islands (Denmark)Not requiredNoneNoneNot applicableNot applicable
FijiIf traveling from an endemic zone and >1 year of age, and within 10 days of having stayed overnight or longer in an endemic zone.NoneNoneNot applicableNot applicable
FinlandNot requiredNoneNoneNot applicableNot applicable
FranceNot requiredNoneNoneNot applicableNot applicable
French GuianaRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageRisk in all areas except no risk on Devil’s Island (Ile du Diable) and the other coastal islands.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
French Polynesia, includes the island groups of Society Islands (Tahiti, Moorea, and Bora-Bora); Marquesas Islands (Hiva Oa and Ua Huka); and Austral Islands (Tubuai and Rurutu)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
GabonRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Gambia, TheIf traveling from an endemic zone and >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
GeorgiaNot requiredNoneRisk in southeastern part of the country near Azerbaijan border and Kura River and risk in the districts of Gardabanis, Marneulis, and Sighnaghis in the Kakheti and Kveno Kartli regions. No risk in Tbilisi.NoneChloroquine
GermanyNot requiredNoneNoneNot applicableNot applicable
GhanaRequired upon arrival from all countriesFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Gibraltar (U.K.)Not requiredNoneNoneNot applicableNot applicable
GreeceNot requiredNoneNoneNot applicableNot applicable
Greenland (Denmark)Not requiredNoneNoneNot applicableNot applicable
GrenadaIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Guadeloupe, including St. Barthelemy and Saint Martin (France)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Guam (U.S.)Not requiredNoneNoneNot applicableNot applicable
GuatemalaIf traveling from an endemic zone and >1 year of ageNoneRural areas only at altitudes below 1,500 m (<4,921 ft). No risk in Guatemala City, Antigua or Lake Atitlán.NoneChloroquine
GuineaIf traveling from an endemic zone and >1 year of age.For all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Guinea-BissauIf traveling from an endemic zone and >1 year of age.

Required also for travelers arriving from:

Africa: Angola, Benin, Burkina Faso, Burundi, Cape Verde, Central African Republic, Chad, Congo, Côte d’Ivoire, Democratic Republic of Congo, Djibouti, Equatorial Guinea, Ethiopia, Gabon, Gambia, Ghana, Guinea, Kenya, Liberia, Madagascar, Mali, Mauritania, Mozambique, Niger, Nigeria, Rwanda, São Tomé and Principe, Senegal, Sierra Leone, Somalia, Tanzania, Togo, Uganda, and Zambia.

Americas: Bolivia, Brazil, Colombia, Ecuador, French Guiana, Guyana, Panama, Peru, Suriname, and Venezuela.

For all travelers >9 months of age.AllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Guyana

If traveling from an endemic zone.

Required also for travelers arriving from:

Africa: Angola, Benin, Burkina Faso, Burundi, Cameroon, Central African Republic, Chad, Congo, Côte d’Ivoire, Democratic Republic of Congo, Gabon, Gambia, Ghana, Guinea, Guinea- Bissau, Kenya, Liberia, Mali, Niger, Nigeria, Rwanda, São Tomé and Principe, Senegal, Sierra Leone, Somalia, Tanzania, Togo, and Uganda

 

Americas: Belize, Bolivia, Brazil, Colombia, Costa Rica, Ecuador, French Guiana, Guatemala, Honduras, Nicaragua, Panama, Peru, Suriname, and Venezuela

For all travelers >9 months of age.Risk in all rural areas below 900 m (<2,953 ft)ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
HaitiIf traveling from an endemic zoneNoneAllNoneChloroquine
HondurasIf traveling from an endemic zoneNoneRisk throughout the country at altitudes below 1000 m (<3,281 ft) and in Roatán and other Bay Island. Risk exists in the outskirts of Tegucigalpa and San Pedro Sula.NoneChloroquine
Hong Kong SAR (China)Not requiredNoneNoneNot applicableNot applicable
HungaryNot requiredNoneNoneNot applicableNot applicable
IcelandNot requiredNoneNoneNot applicableNot applicable
India

If traveling from an endemic zone.

Required also for travelers arriving from or transiting:

Africa: Angola, Benin, Burkina Faso, Burundi, Cameroon, Central African Republic, Chad, Congo, Côte d’Ivoire, Democratic Republic of Congo, Equatorial Guinea, Ethiopia, Gabon, Gambia, Ghana, Guinea, Guinea- Bissau, Kenya, Liberia, Mali, Niger, Nigeria, Rwanda, São Tomé and Principe, Senegal, Sierra Leone, Somalia, Sudan, Togo, Uganda, Tanzania, and Zambia

Americas: Bolivia, Brazil, Colombia, Ecuador, French Guiana, Guyana, Panama, Peru, Suriname, and Venezuela

Caribbean: Trinidad and Tobago

Any person (except infants ≤6 months) arriving without a certificate within 6 days of departure from or transit through an endemic area will be isolated for up to 6 days.3

NoneRisk in all areas throughout country except no risk in areas above 2,000 m (>6,561 ft) in Himachal Pradesh, Jammu, Kashmir, and Sikkim. Risk also exists in urban areas below 2000 m, including Delhi and Mumbai (Bombay).ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
IndonesiaIf traveling from an endemic zoneNoneRisk in rural Sumatra, Sulawesi, Kalimantan and Nusa Tenggara Barat. No risk in urban areas.Risk in all areas of eastern Indonesia (provinces of Papua Indonesia, Irian Jaya Barat, Nusa Tenggara Timur, Maluku, and Maluku Utara).

No risk in Jakarta, resort areas of Bali and the island of Java, except for the Menoreh Hills in central Java.

ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
IranIf traveling from an endemic zoneNoneRisk in rural areas of Sistan- Baluchestan, the southern tropical part of Kerman, and Hormozgan province. Risk in Ardebil and East Azerbijan provinces north of the Zagros mountains during March through November.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
IraqIf traveling from an endemic zoneNoneRisk in Basrah province and in areas at altitudes below 1,500 m (<4,921 ft) in provices of Duhok, Erbil, Ninawa, Sulaimaninya, and Ta’mim. No risk in Baghdad, Tikrit, and Ramadi.NoneChloroquine
IrelandNot requiredNoneNoneNot applicableNot applicable
IsraelNot requiredNoneNoneNot applicableNot applicable
ItalyNot requiredNoneNoneNot applicableNot applicable
Jamaica

If traveling from an endemic zone and >1 year of age

None

Very limited risk in Kingston; therefore prophylaxis is not recommended.

None

None

JapanNot requiredNoneNoneNot applicableNot applicable
JordanIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
KazakhstanIf traveling from an endemic zoneNoneNoneNot applicableNot applicable
KenyaIf traveling from an endemic zone and >1 year of ageFor all travelers >9 months of age. The cities of Nairobi and Mombasa have lower risk of transmission than rural areas.Risk in all areas (including game parks) at altitudes below 2,500 m (<8,202 ft). No risk in Nairobi.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Kiribati (formerly Gilbert Islands), includes Tarawa, Tabuaeran (Fanning Island), and Banaba (Ocean Island)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
KosovoNot requiredNoneNoneNot applicableNot applicable
KuwaitNot requiredNoneNoneNot applicableNot applicable
KyrgyzstanNot requiredNoneRisk in some southern and western parts of the country, mainly in the provinces of Batken, Osh, and Jalal-Abad in the areas bordering Tajikistan and Uzbekistan. Risk also in the capital city Bishkek.NoneChloroquine
LaosIf traveling from an endemic zoneNoneAll, except no risk in the city of Vientiane.ConfirmedOnly atovaquone/ proguanil or doxycycline in the provinces of Bokèo and Louang Namtha along the Laos- Burma border and along the Laos- Thailand border in the province of Saravane and Champassack. All other areas atovaquone/ proguanil, doxycycline, or mefloquine (See Map 4-9).
LatviaNot requiredNoneNoneNot applicableNot applicable
LebanonIf traveling from an endemic zoneNoneNoneNot applicableNot applicable
LesothoIf traveling from an endemic zoneNoneNoneNot applicableNot applicable
LiberiaRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
LibyaIf traveling from an endemic zoneNoneNoneNot applicableNot applicable
LiechtensteinNot requiredNoneNoneNot applicableNot applicable
LithuaniaNot requiredNoneNoneNot applicableNot applicable
LuxembourgNot requiredNoneNoneNot applicableNot applicable
Macau SAR (China)Not requiredNoneNoneNot applicableNot applicable
MacedoniaNot requiredNoneNoneNot applicableNot applicable
MadagascarIf traveling from an endemic zoneNoneAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Madeira Islands (Portugal)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
MalawiIf traveling from an endemic zoneNoneAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
MalaysiaIf traveling from an endemic zone and >1 year of age. A certificate is also required from travelers who have transited an endemic area within the preceding 6 days.NoneRisk in rural areas, particularly in the forested, hilly, and underdeveloped interior areas. No risk in urban and coastal areas. Note: No risk in Republic of Singapore.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
MaldivesIf traveling from an endemic zoneNoneNoneNot applicableNot applicable
MaliRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Malta

If traveling from an endemic zone and >9 months of age.

Children <9 months of age arriving from an endemic zone may be subject to isolation or surveillance.

NoneNoneNot applicableNot applicable
Marshall IslandsNot requiredNoneNoneNot applicableNot applicable
Martinique (France)Not requiredNoneNoneNot applicableNot applicable
MauritaniaRequired upon arrival from all countries if traveler is >1 year of age. Exception: Not required for travelers from a non-endemic zone who stay <2 weeksFor all travelers >9 months of ageAll, except no risk in Dakhlet- Nouadhibou and Tiris-Zemmour region.ProbableAtovaquone/ proguanil, doxycycline, or mefloquine
MauritiusIf traveling from an endemic zoneNoneRural only. No risk on Rodrigues Island.NoneChloroquine
Mayotte (French territorial collectivity)Not requiredNoneAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
MexicoNot requiredNoneRisk is limited to areas infrequently visited by travelers including small foci along the Guatemala and Belize borders in the states of Chiapas, Quintana Roo, and Tabasco; rural areas in the states of Nayarit, Oaxaca, Sinaloa; and in an area between 24°N and 28°N latitude, and 106°W and 110°W longitude, which lies in parts of Sonora, Chihuahua, and Durango. No malaria risk exists along the United States-Mexico border. No malaria risk exists in the major resorts along the Pacific and Gulf coasts.

Risk is very limited; therefore, prophylaxis is not recommended for most travelers to Mexico. Travelers should use personal protection measures such as insect repellents for malaria prevention. Chemoprophylaxis is recommended for the rare traveler going to the risk areas.

NoneChloroquine
Micronesia, Federated States of; Includes Yap Islands, Pohnpei, Chuuk, and KosraeNot requiredNoneNoneNot applicableNot applicable
MoldovaNot requiredNoneNoneNot applicableNot applicable
MonacoNot requiredNoneNoneNot applicableNot applicable
MongoliaNot requiredNoneNoneNot applicableNot applicable
MontenegroNot requiredNoneNoneNot applicableNot applicable
Montserrat (U.K.)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
MoroccoNot requiredNoneRisk in rural areas of Chefchaouen province. No risk in Tangier, Rabat, Casablanca, Marrakech, and Fès. Risk is very limited; therefore, prophylaxis is not recommended.NoneNone
MozambiqueIf traveling from an endemic zone and >1 year of age NoneAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
NamibiaIf traveling from an endemic zone and >1 year of age. Required also for travelers on unscheduled flights who have transited an infected area. Children <1 year of age may be subject to surveillance.NoneRisk in the provinces of Kunene, Ohangwena, Okavango, Omaheke, Omusati, Oshana, Oshikoto, Otjozondjupa, and the Caprivi Strip.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
NauruIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
NepalIf traveling from an endemic zoneNoneRisk in rural areas at altitudes below 1,200 m (<3,937 ft) in the Tarai and Hill districts bordering India and in the areas of the inner Tarai valley areas of Udaypur Sindhupalchowk, Makwanpur, Chitwan, and Dang. No risk in Kathmandu or on typical Himalayan treks.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Netherlands Antilles (Bonaire, Curaçao, Saba, St. Eustasius, and St. Maarten)If traveling from an endemic zone and >6 months of age3NoneNoneNot applicableNot applicable
NetherlandsNot requiredNoneNoneNot applicableNot applicable
New Caledonia (France)

If traveling from an endemic zone and >1 year of age.

Note: In the event of an epidemic threat to the territory, a specific vaccination certificate may be required.

NoneNoneNot applicableNot applicable
New ZealandNot requiredNoneNoneNot applicableNot applicable
NicaraguaIf traveling from an endemic zone and >1 year of ageNoneRisk in rural areas and in outskirts of Managua.NoneChloroquine
NigerRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
NigeriaIf traveling from an endemic zone and >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Niue (New Zealand)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Norfolk Island (Australia)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Korea, NorthNot requiredNoneLimited malaria risk in some southern areas.NoneChloroquine
Northern Mariana Islands (U.S.), includes Saipan, Tinian, and Rota IslandNot requiredNoneNoneNot applicableNot applicable
NorwayNot requiredNoneNoneNot applicableNot applicable
OmanIf traveling from an endemic zoneNoneLimited risk in remote areas of Musandam Province. Risk is very limited; therefore, prophylaxis is not recommended.ConfirmedNone
PakistanIf traveling from an endemic zone. Not required for infants <6 months of age if the mother’s certificate shows she was vaccinated before the child’s birth.3NoneRisk in all areas (including all cities) at altitudes below 2,000 m (<6,562 ft).ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
PalauIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
PanamaIf traveling from an endemic zoneFor all travelers >9 months of age traveling to the provinces of Darien, Kunayala (San Blas) and Panama (see Map 4-16), excluding the Canal Zone, Panama City and the San Blas Islands.Risk exists in rural areas of Bocas Del Toro, Darién, San Blas provinces and San Blas Islands. No risk in Panama City or in the former Canal Zone.Confirmed in Darién and San Blas provinces, including San Blas islands.Chloroquine in Bocas Del Toro. Atovaquone/ proguanil; doxycycline; or mefloquine in Darién and San Blas.
Papua New GuineaIf traveling from an endemic zone and >1 year of ageNoneRisk throughout at altitudes below 1,800 m (<5,906 ft).ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Paraguay

If traveling from an endemic zone

For all travelers >9 months of age traveling to all areas of Paraguay.

Risk in the departments of Alto Paraná, Caaguazú, and Canendiyú.

None

Chloroquine

PeruNot requiredFor all travelers >9 months of age traveling to the areas east of the Andes Mountains (see Map 4-16). Travelers who are limiting travel to the cities of Cuzco and Machu Picchu do not need vaccination. Peru recommends vaccination for those who intend to visit any jungle areas of the country <2,300 m (<7,546 ft.).Risk in all departments below 2000 m (6,561 ft) except no risk in Arequipa, Moquegua, Puno, and Tacna. Risk in Puerto Maldonado. Travelers who will visit only in Lima and its vicinity, coastal areas south of Lima, or the highland tourist areas (Cuzco, Machu Picchu, and Lake Titicaca) are not at risk and need no prophylaxis.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
PhilippinesIf traveling from an endemic zone and >1 year of ageNoneRisk exists in areas below 600 m (<1,969 ft), except no risk in Bohol Island, Borocay Island, Catanduanes Island, and Cebu Island. No risk is considered to exist in Manila or other urban areas.Confirmed for P. falciparumAtovaquone/ proguanil, doxycycline, or mefloquine
Pitcairn Islands (U.K.)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
PolandNot requiredNoneNoneNot applicableNot applicable
PortugalRequired only for travelers >1 year of age arriving from an endemic zone and destined for the Azores and Madeira. However, no certificate is required for travelers in transit at Funchal, Santa Maria, and Porto Santo.NoneNoneNot applicableNot applicable
Puerto Rico (U.S.)Not requiredNoneNoneNot applicableNot applicable
QatarNot requiredNoneNoneNot applicableNot applicable
Réunion (France)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
RomaniaNot requiredNoneNoneNot applicableNot applicable
RussiaNot requiredNoneNoneNot applicableNot applicable
RwandaRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Saint Helena (U.K.)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Saint Kitts (Saint Christopher) and Nevis (U.K.)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Saint LuciaIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Saint Pierre and Miquelon (France)Not requiredNoneNoneNot applicableNot applicable
Saint Vincent and the GrenadinesIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Samoa (formerly Western Somoa)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
San MarinoNot requiredNoneNoneNot applicableNot applicable
São Tomé and PríncipeRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Saudi ArabiaIf traveling from an endemic zoneNoneRisk in Al Bahah, Al Madinah, Asir (excluding the highaltitude areas above 2,000 m), Jizan, Makkah, Najran, and Tabuk province. No risk in urban areas of Jeddah, Mecca, Medina, and Ta’if.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
SenegalIf traveling from an endemic zoneFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
SerbiaNot requiredNoneNoneNot applicableNot applicable
SeychellesIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Sierra LeoneRequired upon arrival from all countriesFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
SingaporeIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
SlovakiaNot requiredNoneNoneNot applicableNot applicable
SloveniaNot requiredNoneNoneNot applicableNot applicable
Solomon IslandsIf traveling from an endemic zoneNoneRisk in all areas except for the southern province of Rennell and Bellona, the eastern province of Temotu, and the outer islands of Tikopia, Anuta, and Fatutaka.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
SomaliaIf traveling from an endemic zoneFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
South AfricaIf traveling from an endemic zone and >1 year of ageNoneRisk exists in the low-altitude areas of the Mpumalanga Province, Northern Province (Limpopo), and northeastern Kwa- Zulu-Natal as far south as the Tugela River. Risk in Kruger National Park.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
South Georgia & South Sandwich IslandsNot requiredNoneNoneNot applicableNot applicable
Korea, South Not requiredNoneRisk limited to demilitarized zone (DMZ) and to rural areas in the northern parts of Kyonggi and Kangwon provinces.NoneChloroquine
South Sandwich IslandsNot requiredNoneNoneNot applicableNot applicable
SpainNot requiredNoneNoneNot applicableNot applicable
Sri LankaIf traveling from an endemic zone and >1 year of ageNoneRisk in all areas, except no risk in the districts of Colombo, Galle, Kalutara, and Nuwara Eliya.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
SudanIf traveling from an endemic zone and >1 year of age. May be required for travelers leaving Sudan.For all travelers >9 months of ageAllConfirmed

Atovaquone/ proguanil, doxycycline, or mefloquine

SurinameIf traveling from an endemic zoneFor all travelers >9 months of age.Risk in all areas, except no risk in Paramaribo and coastal districts of Nickerie, Coronie, Saramacca, Wanica, Commewijne, and Marowijne north of latitude 5°N.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
SwazilandIf traveling from an endemic zoneNoneRisk in the northern and eastern lowland areas bordering Mozambique in the Lubombo district, particularly around the villages/towns of Big Bend, Mhlume, Simunye, and Tshaneni.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
SwedenNot requiredNoneNoneNot applicableNot applicable
SwitzerlandNot requiredNoneNoneNot applicableNot applicable
SyriaIf traveling from an endemic zoneNoneRisk along the northern border in El Hassaka province.NoneChloroquine
TaiwanNot required. (Updated February 6, 2008)NoneNoneNot applicableNot applicable
TajikistanNot requiredNoneRisk in all areas below 2,500 m (<8,202 ft) particularly along the southern border in Khatlon Oblast; central (Dushanbe), western (Gorno- Badakhshan), and northern (Leninabad) areas.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
TanzaniaIf traveling from an endemic zone and >1 year of age (Updated July 29, 2008)For all travelers >9 months of age. The city of Dar es Salaam has a lower risk of transmission than rural areasAll areas at altitudes below 1,800 m (<5,906 ft).

Confirmed

Atovaquone/ proguanil, doxycycline, or mefloquine

ThailandIf traveling from an endemic zone and >1 year of ageNoneRisk in rural areas that border Cambodia, Laos, and Myanmar (Burma). Very limited risk in Phang Nga and Phuket therefore prophylaxis is not recommended for these two areas. No risk in cities and in major tourist resorts. No risk in Bangkok, Chiang Mai, Chiang Rai, Pattaya, Koh Samui, and Koh Phangan. (Updated September 19, 2007)ConfirmedAtovaquone/ proguanil or doxycycline. (see Map 4-9).
Timor-Leste (East Timor)Required for travelers coming from an endemic zoneNoneAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
TogoRequired upon arrival from all countries if traveler is >1 year of ageFor all travelers >9 months of ageAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
Tokelau (New Zealand)Not requiredNoneNoneNot applicableNot applicable
TongaIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
Trinidad and TobagoIf traveling from an endemic zone and >1 year of ageFor all travelers >9 months of age whose itinerary includes Trinidad. Port of Spain has lower risk of transmission than rural or forested areas. Cruise ship passengers who do not disembark from the ship or travelers visiting only the urban area of Port of Spain (including passengers in-transit only) may consider foregoing vaccination. Vaccination is NOT recommended for those visiting only Tobago. (Updated February 17, 2009)NoneNot applicableNot applicable
TunisiaIf traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
TurkeyNot requiredNoneRisk in the provinces of Adana, Adryaman, Batman, Bingol, Bitlis, Diyarbakar, Elazig, Gaziantep, Hakkari, Hatay, Icel, Kahraman Maras, Kilis, Mardin, Mus, Osmaniyeh, , Sanliurfa, Siirt, Sirnak, and Van. No risk on the Incirlik U.S. Air Force base and on typical cruise itineraries.NoneChloroquine
TurkmenistanNot requiredNoneRisk in southeast Mary Region and in the flood plains between the Murgab and Tedzhen Rivers.NoneChloroquine
Turks and Caicos Islands (U.K.)If traveling from an endemic zone and >1 year of ageNoneNoneNot applicableNot applicable
TuvaluNot requiredNoneNoneNot applicableNot applicable
UgandaIf traveling from an endemic zone and >1 year of ageFor all travelers >9 months of age.AllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
UkraineNot requiredNoneNoneNot applicableNot applicable
United Arab EmiratesNot requiredNoneNoneNot applicableNot applicable
United Kingdom (with Channel Islands and Isle of Man)Not requiredNoneNoneNot applicableNot applicable
United StatesNot requiredNoneNoneNot applicableNot applicable
UruguayIf traveling from an endemic zoneNoneNoneNot applicableNot applicable
UzbekistanNot requiredNoneSporadic cases reported in Uzunskiy, Sariassiskiy, and Shurchinskiy districts (Surkhanda-Rinskaya Region).NoneChloroquine
VanuatuNot requiredNoneAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
VenezuelaNot requiredFor all travelers >9 months of age traveling to Venezuela, except the northern coastal area (see Map 4-16). The cities of Caracas and Valencia are not in the endemic zone.Risk exists in rural areas of the following states: Apure, Amazonas, Barinas, Bolivar, Sucre, Tachira, and Delta Amacuro. Risk in Angel Falls.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
VietnamIf traveling from an endemic zone and >1 year of ageNoneRural only, except no risk in the Red River delta and the coastal plain north of the Nha Trang. No risk in Hanoi, Ho Chi Minh City (Saigon), Da Nang, Nha Trang, Qui Nhon, and Haiphong.ConfirmedOnly atovaquone/ proguanil or doxycycline in the southern part of the country in the provinces of Tay Ninh, Song Be, Lam Dong, Ninh Thuan, Khanh Hoa, Dac Lac, Gia Lai, and Kon Tum. All other areas atovaquone/ proguanil, doxycycline, or mefloquine (see Map 4-9).
Virgin Islands, BritishNot requiredNoneNoneNot applicableNot applicable
Virgin Islands, U.S.Not requiredNoneNoneNot applicableNot applicable
Wake Island, U.S.Not requiredNoneNoneNot applicableNot applicable
Western SaharaNot requiredNoneRisk is very limited; therefore, prophylaxis is not recommended.NoneNone
YemenIf traveling from an endemic zone and >1 year of ageNoneAll areas at altitudes below 2,000 m (<6,561 ft). No risk in Sana’a.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
ZambiaNot requiredNoneAllConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine
ZimbabweIf traveling from an endemic zone and >1 year of ageNoneAll, except no risk in cities of Harare and Bulawayo.ConfirmedAtovaquone/ proguanil, doxycycline, or mefloquine

1Yellow fever vaccine entry requirements are necessary for travelers to comply with in order to enter the country. In general, these are in place to prevent importation and transmission of yellow fever virus. Countries requiring yellow fever vaccination for entry adhere to the regulations put forth by WHO as stated in the International Health Regulations. Some countries require vaccination for travelers coming from an endemic zone. “Traveling from an endemic zone” is defi ned as transit through an endemic zone in the previous 6 days. Country requirements are subject to change at any time; therefore, CDC encourages travelers to check with the appropriate embassy or consulate prior to departure.

2The information in the section on yellow fever vaccine recommendations is advice given by CDC to prevent yellow fever infections among travelers.

3Please note, the U.S. Advisory Committee on Immunization Practices recommends avoiding vaccination of infants.

4Recommendations are subject to change at any time if disease conditions change; therefore, CDC encourages travelers to check for relevant travel notices on the website wwwn.cdc.gov/travel prior to departure.

Note: Country requirements are subject to change at any time; therefore, CDC encourages travelers to check with the appropriate embassy or consulate prior to departure.

  • Content source:
    Division of Global Migration and Quarantine
    National Center for Preparedness, Detection, and Control of Infectious Diseases
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