Physicochemical
RNA, Double Strand
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10
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(S)
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RNA; total MW = 12.1 - 15.1 x 10^6 (14)
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(S)
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(S)
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Stability of Infectivity (effects) |
labile at pH 3.0; partial or complete resistance to lipid solvents (3-5)
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1:5
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about 0.2 dex loss
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4.0 dex
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4.0 dex (5)
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chloroform treatment caused a 100-fold reduction in mouse ED50 (5)
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Virion Morphology |
icosahedral shape
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75 nm (4)
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nm
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nm
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negative contrast electron microscopy
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no envelope
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capsid = 5.3 nm (3); contains 32 capsomeres
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Morphogenesis |
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Hemagglutination |
Yes and No
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concentrated infective Vero culture fluid (23)
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various*
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5.5 - 8.0
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7.0 - 8.0
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4dC, RT, 37dC
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HA optimal in presence of 0.6M NaCl
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HI, CF, NT (nb mice), PRNT, afar-gel precipitation
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HA optimal in presence of 0.6M NaCl
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