| | | Related to but perhaps not identical with the South Dakota strain (serotype 2) of EHD isolated in 1956 [2] ; not related to Korean hemorrhagic fever, or to the Bucyrus strain of equine arteritis virus [2] . | | Originally, this agent was compared by CF with at least 150 arboviruses and no overlap was noted. Among those compared are the following: By CF, using immune sera (two-fold dilutions from 4 to 128) for a large number of arboviruses and New Jersey EHD antigen (4, 8 and 16 units) no overlap was found with any of the following sera: 15 Group A (homologous titers from 32 to 512); 33 Group B (32 to 512); 7 Group C (32 to 128); 10 from Bunyamwera group (32 to 512); 4 from California group (64 to 128); 4 from Guama group (64 to 128). Nor was there an overlap with any of the following grouped or ungrouped viruses' sera: Capim (128), Guajara (256), Bushbush (128), Bwamba (512), Simbu (64), Oropouche (16), Sathuperi (128), Turlock (64), Umbre (32), Anopheles A (64), Lukuni (64), Bakau (128), Ketapang (128), Koongol (64), Wongal (64), Vesicular Stomatitis, New Jersey (128), Vesicular Stomatitis, Indiana (128), Quaranfil (512), Chenuda (256), Nyamanini (256), Triniti (64), Ieri (32), Aruac (32), Rift Valley fever (256), Colorado tick fever (128), Wad Medani (256), SF Sicilian (128), Hart Park (32), Anopheles B (128), Tacaiuma (64), Manzanilla (256), Piry (128), Witwatersrand (256), Akabane (512), Tacaribe (256), Junin (32), Mossuril (64), SF Naples (64), and a few additional as yet undecribed viruses. (N.E. Mettler and J. Casals, personal communication.) | | Antigenically distinguishable from bluetongue virus (BTB) by complement-fixation, plaque-reduction neutralization, immunofluorescence, and afar-gel precipitation, although cross reactivity has been shown to some degree in some circumstances ( [5] , [6] , [7] ). | | Two-way cross relationships between Ibaraki virus and EHD virus, serotypes 1 and 2, demonstrated by agar-gel precipitin and indirect fluorescent antibody tests [12] . By neutralization tests, Ibaraki virus was more closely related to EHD virus, serotype 2 (Alberta strain). Antigenic relationship not observed between Ibaraki virus and four serotypes of bluetongue found in USA. | | Related by complement-fixation tests to other members of the orbivirus group, namely bluetongue, Ibaraki and Eubenangee viruses [5] , [8] . | | Antigenic relationships demonstrated between BLU, EHD, and Abadina viruses by CF and agar-gel precipitin tests [19] . | | High-titered antibody to an Australian isolate of BLU cross-reacted at low titer, by CF, with EHD and Eubenangee virus antigens [20] . | | Immunological cross-reaction documented between virus-specified tubules of BLU and EHD viruses [21] . | | Presently the EHD serogroup consists of EHD and Ibaraki viruses. | | |
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