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  Ganjam   GANV

Possible Arbovirus

No


Other Information
USDA Restricted 

Nairobi Sheep Disease
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
Related to IG 3159 by CF tests. By CF, a serum to Ganjam virus (homol.>512) did not react with Farallon, Chenuda, Colorado tick fever, Hughes, Dugbe, Bhanja, Wanowrie, Kaisodi, Kemerovo, Johnston Atoll, Lanjan, Nyamanini, Manawa, Quaranfil, Silverwater, Soldado, Thogoto, Lipovnik, Uukuniemi, Wad Medani, NDV.
BY CF Ganjam virus antigen did not react with (homol. titer in parenthesis) Farallon (256), Chenuda (256), Colorado tick fever (64), Hughes (512), Bhanja (512), Wanowrie (512), Soldado (256). Thogoto (128), Uukuniemi(256), Wad Medani (128), Piry (>128), Acara (64), Pacui (64), Irituia (64), Akabane (>16), Hart Park (8), Mossuril (32), Ingwavuma (>16), Palyam (32), Wongal(32), Mapputa(64), Witwatersrand (32), Tacaribe (>16), Tete (8), Junin (8), Tacaiuma (128), Anopheles B (64), Candiru (64), Navarro (64), Lebombo (64), Sicilian (>128), EHD-NJ(64), VSNJ (32), VS-Indiana (32), Bwamba (SE493) (64), Anopheles A (32), Lukuni (>128), Jurona (32), Nyando (32), Oropouche (256), and grouping sera for Bunyamwera, California, Simbu and Capim groups.
By HI a serum to Ganjam virus (homol. CF >512) did not inhibit Bhanja (IbAr 2709), 11 group A viruses, 13 group B viruses, Marituba, Oriboca, Caraparu, Bunyamwera, Germiston, Ilesha, Tahyna, California, Bwamba, Sathuperi, Ketapang, Bakau, Manzanilla, Witwatersrand, Naples, Sicilian, Koongol, Akabane, Ingwavuma, Tacaiuma, Umbre. (This information from the WHO International Reference Centre.)
Distantly related by CF test to Dugbe virus [10] .
Ed. Note: It has been found that a close relationship exists between Nairobi sheep disease and Ganjam viruses as demonstrated by IFA and CF tests (F.G. Davies and J. Casals, personal communication). Ganjam virus is now considered to be a strain of Nairobi sheep disease virus [18] .
A low-titered relationship by CF, IFA, and indirect HA demonstrated between CON and NSD viruses [12] , [13] . SIRACA has decided that these relationships are no greater than those used to establish the BUN. Supergroup. The CON and NSD antigenic groups should be kept as two distinct serogroups. Subsequently, intergroup antigenic relationships were demonstrated among viruses of CHF-CON, DGK, HUG, NSD, QYB, and SAK serogroups. Relationships were demonstrated by IFA, NT, and HI tests [19] . On the basis of these serologic findings as well as biochemical and molecular studies, these viruses were assigned genus status (Nairovirus) within the family Bunyaviridae [20] .
 
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