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  Hazara   HAZV

Possible Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
 

CHF-CON
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
Hyperimmune mouse serum to HAZ virus (homologous titer = 320) did not react in the HI test with 27 arbovirus antigens including 8 members of group A, 13 of group B, 4 of group C, and 2 others. HAZ hyperimmune mouse serum (homologous titer = 128) did not react in the CF test with antigens of 81 arboviruses, and of hepatoencephalitis virus and normal mouse brain [1] .
HAZ virus found to be related to, but distinct from the Congo virus by NT and CF tests [2] , [3] , [5] , also by HI [4] .
A low-titered relationship by CF, IFA and indirect HA was demonstrated between CHF-CON and NSD viruses [6] , [7] . SIRACA has decided that these relations are no greater than those used to establish BUN Supergroup. The CHF-CON and NSD antigenic groups should be kept as two distinct serogroups.
Following the above observations, intergroup relationships were demonstrated for members of the above two serogroups as well as for members of the DGK, HUG, QYB and SAK serogroups [8] .
 
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