| | | No evidence of a serological relationship between Ibaraki virus and bluetongue virus was recognized. Cross neutralization was not observed and cross complement-fixation was not shown between Ibaraki and bluetongue, type 10 [4] , [6] . By CF, sheep antisera to bluetongue, types 1-16 which reacted with bluetongue, type 10 antigen, were negative with Ibaraki antigen [4] . Studies conducted elsewhere, employing neutralization tests in mice, BHK-21 and other cell culture systems, complement-fixation, and ferritin tagged antibody, also confirmed a lack of antigenic relationship between Ibaraki and bluetongue viruses [10] . Two-way cross relationships between Ibaraki virus and EHD virus, serotypes 1 and 2, demonstrated by agar gel precipitin and indirect fluorescent antibody tests [12] . By neutralization tests, Ibaraki virus was more closely related to EHD virus, serotype 2 ("Alberta strain"). Antigenic relationship not observed between Ibaraki virus and four serotypes of bluetongue found in USA. | | |
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