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  Isfahan   ISFV

Probable Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
 

Vesicular Stomatitis
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
 
Results of Plaque Reduction Neutralization Tests [1]
Virus
Immune Serum VSNJ VSI COC PIRY CHP ISF


* Reciprocal of highest serum dilution producing >95% plaque inhibition.
** Prepared in a guinea pig sequentially inoculated with Piry Chandipura, Indiana, New Jersey, and Cocal viruses.
Note: All immune sera prepared in guinea pigs receiving 2-5 subcutaneous injections of live virus at 14-day intervals.
VSNJ 10240 * <10 <10 <10 <10 <10
VSI <10 327680 320 <10 <10 <10
COC <10 160 5120 <10 <10 <10
VSA <10 20 20 <10 <10 <10
PIRY <10 <10 <10 10240 <10 <10
CHP <10 <10 <10 <10 10240 <10
ISF <10 <10 <10 <10 <10 2560
Group
VSV ** 640 2560 160 5120 1280 40
 
Results of Complement Fixation Tests [2]
Antibody
ISF ISF GP CHP Piry
Antigen MIAF Serum MIAF IMS


Antibody titer/antigen titer
Isfahan 1024/1024 256/256 16/16 8/4
Chandipura
(I 653514) 64/256 32/16 256/1024 16/64
Chandipura
(IbAn 9978) 32/256 32/16 256/1024 16/16
Piry 64/16 8/4 16/4 512/64
Flanders
(Control) 4/<4 <4/<4 <4/<4 <4/<4
In other CF tests, ISF antigen (8 units) and guinea pig antiserum were negative when tested against VSNJ (homologous serum titer = 128), VSI (2048) and COC (128) viruses. Also, ISF antigen did not react with VSA antiserum (200) [1] .
 
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