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Abbreviations
Information Exchange

Virus Name: Main Drain

Abbreviation: MDV

Status
Arbovirus

Select Agent
No

SALS Level
2

SALS Basis
Results of SALS surveys and information from the Catalogue.

Other Information

Antigenic Group
Bunyamwera

Section V - Antigenic Relationship and Lack of Relationship to Other Viruses

See Reference [6] .

Main Drain Antigen
		CF ¹	HI ¹	NT ²	Main Drain antiserum
Type of ImmuneFluid	Immune Fluid or Antigen	Ht/Ho ³	Ht/Ho	Ht/Ho	CF ¹	HI ¹	NT ²


¹ CF and HI titers are expressed as the reciprocal of the serum or ascitic fluid dilution.
² NT results are expressed as LNI given in dex. Tests with hyperimmune sera or ascitic fluids were performed in SM inoculated ic, whereas tests with immune hamster serum were done by plaque reduction in Vero cells.
³ Heterologous titer/homologous titer
⁴ Reagents and facilities of the Yale Arbovirus Research Unit, New Haven, Connecticut, were made available through the courtesy of Dr. W.G. Downs and Dr. R.E. Shope for conducting HI tests. CF tests were done by Dr. R.E. Shope.
Hyperimmune mouse serum or ascitic fluid ⁴	Main Drain	128	1280	2.1	128	1280	2.1
Cache Valley	16/64	0/80		64	0
Lokern	256/512	0/640	0.0/3.7	64	0	0.3
Maguari	32/64	0/320		64	0
Tensaw	256/512	0/1280		64	0
Tlacotalpan	512/512	10/320		64	10
Immune hamster serum	Main Drain		80	2.5		80	2.5
Cache Valley		0/80	0.1/2.1		0	0.0
Lokern		0/160	0.0/3.8		0	0.0
Maguari		0/160	0.2/1.8		0	0.1
Tensaw		10/640	1.2/2.0		0	0.0

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