| | | HA antigen not inhibited by immune serum or ascitic fluid to the following: arboviruses of groups A, B, C, Guama, Bunyamwera, California, and Turlock as well as Sicilian Sandfly fever, Flanders, Silverwater and Colorado tick fever. In addition, no inhibition of HA was demonstrated with immune ascitic fluids to groups A, C, California, Bunyamwera and Pahayokee-Shark River-Gumbo Limbo (Broad). | | CF antigen of AV-782 did not react with immune serum or ascitic fluid to Flanders, yellow fever, St. Louis encephalitis, La Crosse virus, EEE, WEE, Highlands J, Silverwater, Powassan, Tensaw, Colorado tick fever, Turlock, VSNJ, VSI, Cocal, Cowbone Ridge, Tamiami, Anopheles A, Shark River, Pahayokee, trivittatus, Gumbo Limbo, Sawgrass, Newcastle disease virus, encephalomyocar- ditis, mouse hepatitis, mouse adenovirus, LCM and vaccinia. In addition, immune ascitic fluids to broad groups A, B, C, Guama, Bunyamwera, Capim, Phlebotomus fever, and California failed to react with AV-782 antigen. | | IP neutralization tests in suckling mice using another strain of Mermet virus and immune serum to the following did not give evidence of protection: Tensaw, Colorado tick fever, Powassan, Rio Bravo, Modoc, TMA-1381, Kern Canyon, AR-531, CE, EEE, WEE, SLE, Turlock, Flanders, Hart Park and AR-4242. | | | | Cross Reactivities of Mermet (Strain AV-782) Virus with Simbu Group Members (Ht/Ho) |
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| | Mermet Immune Ascitic Fluid | Mermet Antigen |
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| Registered Virus | CF | NT | HI | CF | NT | HI |
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| | | | | | | | | Oropouche | 128/>1024 | /4.3 | | 0/32 | 1.1/3.0 | | | Sathuperi | 8/>1024 | >1.3/4.3 | | 0/128 | 0.3/>6.0 | | | Buttonwillow | 32/>1024 | 2.7/4.3 | | 0/64 | 3.5/3.2 | | | Utinga | 64/>1024 | 1.4/4.3 | | 0/16 | 1.6/2.3 | | | Akabane | 16/>1024 | 0/4.3 | | 0/128 | 0.6/>4.8 | | | Ingwavuma | 512/>1024 | >5.5/4.3 | 20/>1280 | 512/32 | 2.8/3.8 | 10/60 | | Simbu | 8/>1024 | 0.5/4.3 | | 0/16 | 1.3/2.5 | | | Manzanilla | >1024/>1024 | >3.9/4.3 | 40/>1280 | 16/64 | 3.6/>3.9 | 10/80 | | Mermet | >1024 | 4.3 | >1280 | >1024 | 4.3 | >1280 |
| | Mermet virus was shown to be closely related to Ingwavuma and Inini viruses; all three viruses were considered to be subtypes of Manzanilla virus [4] . | | |
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