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Virus Name:
Negishi
Abbreviation:
NEGV
Status
Possible Arbovirus
Select Agent
No
SALS Level
3
SALS Basis
Results of SALS surveys and information from the Catalogue.
Other Information
Antigenic Group
B
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
Negishi antigen or virus
Immune Serum
HI(4)
8 units
CF(4)
NT(1)
RSSE(2i)
40/80
1/2
RSSE(4i)
160/640
1/4
64/256
1/4
1.5/2.7
Powassan(1i)
20/160
1/8
Powassan(4i)
20/640
1/32
32/256
1/8
JE Nak.-NIH(1i)
<20/40
JE Nak.-NIH(4i)
<20/1280
<4/64
0/2.3
MVE(1i)
<20/160
MVE(4i)
<4/128
WN(1i)
<20/640
WN(5i)
<4/128
SLE(1i)
<20/160
SLE(4i)
<4/64
0/2.7
Modoc(1i)
<20/320
Modoc(4i)
40/1280
1/32
<4/128
YF17D(2i)
<20/320
YF17D(5i)
<20/1280
<4/32
NT: LNI given in dex.
Negishi Primary serum
Antigen or Virus
HI(4)
CF(4)
NT(1)
RSSE
20/80
1/4
Powassan
<20/80
JE Nak.-NIH
<20/80
MVE
20/80
1/4
WN
20/80
1/4
SLE
<20/80
Modoc
<20/80
YF 17D
<20/80
Negishi Hyperimmune serum
RSSE
640/1280
1/2
64/128
1/2
2.0/3.0
Powassan
320/1280
1/4
32/128
1/4
JE Nak.-NIH
160/1280
1/8
<4/128
0/3.0
MVE
2560/1280
2/1
4/128
1/32
WN
2560/1280
2/1
16/128
1/8
SLE
640/1280
1/2
16/128
1/8
2.0/3.0
Modoc
80/1280
1/16
<4/128
YF17D
320/1280
1/4
<4/128
The preliminary HI study revealed that the Negishi virus did not relate either to Group A, Group Bunyamwera or Akabane viruses. Above table indicates that the virus is most closely related to the tick-borne complex of B group. Antibody absorption tests carried out in 1961 at RFVL indicated that Negishi virus was a new member of the tick-borne complex since it diverged significantly from both Central European tick-borne encephalitis and louping ill viruses. [9]
In addition, see Reference [11] .
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