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| | 1. | Antigen (or live virus) and immune serum of registered strain of OMSK regularly gives evidence (in HI, CF, NT and cross-immunity tests) of close antigenic relationship to viruses of Group B tick-borne group, including Far East, Siberian, Ural, Central European strains of tick-borne encephalitis virus, diphasic milk-borne fever in USSR, other strains of Omsk Hemorrhagic Fever (Type I and Type II), louping ill (in Scotland), Kyasanur Forest Disease (India), Malayan strain Langat, Japan strain Negishi, Canadian strain Powassan, Homologous titer always higher than heterologous titer in these strains. | | 2. | Antigen or immune serum of registered strain of OMSK in the CF or NT lacks antigenic relationship to viruses of Japanese B encephalitis, West Nile, SLE, EEE, WEE and VEE. | | 3. | Registered strain of virus in HI test (Casals) has antigenic relationship to other members of Group B including viruses of Japanese B encephalitis, SLE, and West Nile. | | 4. | Clark, Delphine, has differentiated two antigenic types of OMSK using agar precipitation and specific adsorption method (HI) (9). From this study two other investigated strains, Bogolubovka (from Dermacentor marginatum) and Guriev (blood from a patient) belong to Type II of OMSK. The registered strain (Kubrin) belongs to Type I. These two types can be distinguished only by these special techniques. | | 5. | According to Casals by use of hyperimmune sera antigenic relationships to other Group B viruses can be demonstrated. | | | For further information on antigenic relationships, see Reference [15] . |
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