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Virus Name: Prospect Hill

Abbreviation: PHV

Status
Probably not Arbovirus

Select Agent
No

SALS Level

SALS Basis

Other Information

Antigenic Group
Hantaan

Section VIII - Susceptibility to Experimental Infection (include viremia)

Experimental host and age	Passage history and strain	Inoculation Route-Dose	Evidence of infection	AST (days)	Titer log10/ml


Balb/c mice (nb)	MP-40 strain, E6/P5	ic 0.01	Develop antibody (IFA)
Mice (nb)		ip
Mice (nb)		sc
Mice (wn)		ic
Mice (wn)		ip
Mice (wn)		im 0.1	Develop antibody (IFA)
Nude mice (NIH:S)		im 0.1	No antibody or antigen
Fischer rat (nb)		ic 0.01	Develop antibody (IFA)
Fischer rat (wn)		im 0.3	Develop antibody (IFA)
Syrian hamster (wn)		im 0.3	Develop antibody (IFA)
Mongolian gerbil (wn)		im 0.3	Develop antibody (IFA)
Meadow vole (nb)		ic 0.01	Specific antibody and antigen
Meadow vole (wn)		im 0.3	in lung tissue 14 days pi
Cynomolgus monkey		iv 10 ml	Viremia day 7, specific antibody; mild proteinuria
Cynomologus monkeys		iv	mild, transient proteinuria and azotemia (5)
Chimpanzee		iv	Mild, transient proteinuria and azotemia (5)

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