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  San Angelo   SAV

Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
 

Califronia
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
No neutralization of San Angelo obtained with WE (1.4 LNI) or SLE (1.7) antisera. No significant neutralization of WE, SLE, ColSK, MM or EMC viruses by San Angelo antiserum (3.8). No HI of WE or SLE viruses by San Angelo antiserum.
Antigenic relationship [1] with immune sera prepared in guinea pigs by multiple ip injections of active virus (except California, BFS-283; immune rabbit serum used in NT was kindly supplied by Dr. W. McD. Hammon).
 
San Angelo Virus Antigen
HI CF NT
Immune Sera or Antigens Ht/Ho Ratio Ht/Ho Ratio Ht/Ho


California (BFS-283) No HA/320 64/256 1/4 2.9/2.0
Trivittatus No HA 8/512 1/64 2.1/4.4
 
San Angelo Virus Immune Serum
HI CF NT
Immune Sera or Antigens Ht/Ho Ratio Ht/Ho Ratio Ht/Ho


California (BFS-283) 320/No HA 64/128 1/2 4.3/3.8
Trivittatus No HA 8/64 1/8 3.3/3.8
Cross CF testing with La Crosse virus and three Texas isolates of California group viruses by Feild, et al. [8] showed the following results.
 
San Angelo Antigen San Angelo Immune Serum
CF CF
Immune Sera or Antigens Ht/Ho Ht/Ho


NT: LNI in dex
La Crosse 256/512 32/64
Houston 46713 32/128 32/64
San Benito 41079 64/64 64/64
Lubbock EM 507 256/512 64/64
For detailed immunologic comparisons with other members of the California complex, refer to the California encephalitis virus registration card of the Arthropod-borne Information Exchange Catalogue and references [2] , [5] , and [6] .
SIRACA considers San Angelo virus as a subtype of California encephalitis virus [13] .
 
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