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Virus Name: Acara

Abbreviation: ACAV

Status
Probable Arbovirus

Select Agent
No

SALS Level
2

SALS Basis
Results of SALS surveys and information from the Catalogue.

Other Information

Antigenic Group
Capim

Section V - Antigenic Relationship and Lack of Relationship to Other Viruses

Acara antigen and immune serum failed to react in CF tests with a large number of known arboviruses as shown in published Catalogue ( [5] ). Acara antiserum failed to inhibit HA of 30 arboviruses ( [5] ).

Acara related by HI and/or CF to members of Capim group as follows:

	Antigen of Registered Virus				Immune Serum of Registered Virus
	HI		CF		HI		CF
Immune Serum	Ht/Ho	Index	Ht/Ho	Index	Antigen	Ht/Ho	Index	Ht/Ho	Index


^* Close to Bushbush
⁺ Tests done by G. Justines
Capim	0/80	0	0/64	0	Capim	0/40	0	0/16	0
Guajar	0/80	0	0/32	0	Guajara	0/40	0	0/16	0
BeAn 20076 ^*	0/80	0	0/32	0	BeAn 20076	0/40	0	0/16	0
Gamboa ⁺	0/320	0		Gamboa	0/20	0
Benfica	0/80	0	16/32	1/2	Benfica	0/40	0	8/16	1/2
Benevies	0/40	0	16/32	1/2	Benevide	0/40	0	16/16	1/1
Morich	40/160	1/4	0/256	0	Moriche	40/40	1/1	0/16	0
Juan Diaz ⁺	10/640	1/64		Juan Diaz	0/20	0	0/8	0

NOTE: MARU 8620 from a sentinel mouse in Panama is very close to Acara.

SIRACA has antigenically classified Acara virus as a distinct virus type and placed it in the Acara complex, one of five complexes comprising the Capim serogroup ( [6] ).

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