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Member of Casal's Group B [9] . As far as is known, WN is not antigenically related to any viruses not in Group B. |
Cross-reactive to a certain extent also in CF, NT and protection challenge with Japanese B and St. Louis viruses, but differentiable from them [5] ; however, cross-absorption studies have shown that WN is no more different from JBW and MVE than are African and American strains of yellow fever. Strains of WN from Africa and India can only be distinguished by very sensitive modification of HI test. |
Spider monkeys inoculated with 17D are protected against West Nile challenge. Rhesus monkey inoculated with SLE followed by Ilheus produced high titered antibodies against WN [11] . Mice immunized with JBE are protected against WN challenge. |
2/6 WN convalescent human sera also protected against yellow fever virus [15] . |
Two independent cross-neutralization studies, employing 42 and 65 flaviviruses, respectively, have confirmed that West Nile is a member of the JBE-MVE-SLE complex within serogroup B [3] , [4] . |
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