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Virus Name/Prototype
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  Bluetongue   BLUV

Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
USDA Permit Required, USDA Restricted, USDA High Consequence Agent 

Bluetongue
Section IV - Virus Properties
Physicochemical
RNA, Double Strand
 

10(31)


(S)




7 (14)

The core has 2 major and 3 minor pooypeptides and is surrounded by outer capsid layer with 2 major polypeptides, No. 2 and 5; No. 2 appears to be main determinate of serotype specificity. (14).

2(12);3(25)

Polypeptide 5A associated with a tubular-like

1.36 gm/cm3 (20) 1.38gm/cm3 in cesium chloride

550 (20)(S)

1.38 (20) 1.42(32) in cesium chloride

470 (20)(S)

Stability of Infectivity (effects)











Resis. to ether, chloroform, deoxycholate; resis. depends on purification (3,10,31)

Virion Morphology

Icosahedral, orbivirus (2)

50-70 nm

nm

nm

Electron microscopy

No envelope present (2); occ. pseudoenvelopes (3)

Capsid diam.: D= 3 nm; L=69 nm (20); 32 capsomeres

Morphogenesis

Cytoplasm

Cytoplasm

Cytoplasm

Cytoplasmic (4)


Hemagglutination

Yes

BHK-21 cell culture; fluoro-carbon ext. + cent. thru sucrose gradients (11,30)

Several (a)

6.0-9.0

6.0-9.0

4dC, 22dC, 37dC

4dC, 22dC, 37dC

(a) Sheep, chicken, goose, guinea pig, mouse erythrocytes

CF, modified direct CF, agar gel precipitin, NT C

(a) Sheep, chicken, goose, guinea pig, mouse erythrocytes
 
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