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Virus Name: California encephalitis

Abbreviation: CEV

Status
Arbovirus

Select Agent
No

SALS Level
2

SALS Basis
Results of SALS surveys and information from the Catalogue.

Other Information

Antigenic Group
California

Section V - Antigenic Relationship and Lack of Relationship to Other Viruses

Originally determined to be new virus on the basis that there were no immunological relationships of any kind between CE virus and the following by the type of test or tests employed (NT, CF and/or vaccination challenge): WEE, EEE, SLE, JBE, WN, YF, ILH, RVF, CTF, ANA, ANB, WYO, BWA, Theiler's TO and GDVII, VSI, VSNJ, and herpes simplex [1] . The CAL group is indirectly related to the BUN group through GRO virus. GRO virus is related to the CAL group by HI (but not CF) and to the BUN group by CF (but not HI) [6] . Members of the CAL group also possess one-way relationships with BUT (SIM group) [7] and PAT (PAT group) viruses [8] . The relationship of members of the CAL group, BUT, and PAT to CE virus follows [6] - [11] .

CE Antigen							CE Antisera
	HI		CF		NT		HI		CF		NT
Immune Sera	Ht/Ho	Ratio	Ht/Ho	Ratio	Ht/Ho	Antigen	Ht/Ho	Ratio	Ht/Ho	Ratio	Ht/Ho


SH=snowshoe hare, LAC=La Crosse, TVT=Trivittatus, KEY=Keystone, SA=San Angelo, JC=Jamestown Canyon, TAH=Tahyna, LUM=Lumbo, MEL=Melao, INK=Inkoo, GRO=Guaroa, BUT=Buttonwillow, PAT=Patois.
SH	640/1280	1/2	32/256	1/8	2.0/5.5	SH	80/320	1/4	64/128	1/2	4.3/3.7
LAC	320/640	1/2	16/64	1/4	3.9/4.0	LAC	80/320	1/4	32/128	1/4	3.0/3.7
TVT			4/128	1/32	4.1/5.5	TVT			8/128	1/16	3.5/5.3
KEY			16/128	1/8		KEY			64/128	1/2
SA			32/64	1/2	4.4/5.0	SA			32/128	1/4	4.0/3.8
JC			8/64	1/8		JC			32/128	1/4
TAH	160/1280	1/8	32/256	1/8	2.4/4.2	TAH	640/640	1	32/128	1/4	3.6/4.1
LUM	320/320	1	64/128	1/2	2.8/4.4	LUM	160/640	1/4	32/128	1/4
MEL			16/256	1/16	2.9/4.8	MEL			32/128	1/4	3.5/5.3
INK			256/512	1/2		INK			8/128	1/16
GRO	10/1280	1/128	0/256	0	1.6/4.3	GRO	10/320	1/32	0/128	0	1.6/5.3
BUT	40/320	1/8	0/128	0	2.0/>3.5	BUT	<10/320	>1/32	0/32	0	0.0/2.5
PAT	<10/160	>1/16	<4/16	>1/4	0.3/>5.4	PAT	10/80	1/8	<4/>64	>1/16

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