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  Gurupi   GURV

Possible Arbovirus

No

3

Isufficient experience with virus; i.e., experience factor from SALS surveys was less than 500 in laboratory facilities with low biocontainment.
Other Information
 

Changuinola
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
Related by CF to Irituia virus (BeAn 28873) of the Changuinola group as follows [2] :
 
Antigen Serum or Ascitic Fluid
Irituia [3i] Gurupi [6i] Ourem [4i] Caninde [5i] Control


a Antibody titer/antigen titer; 0 = <4
Irituia 16/64 a 32/64 64/16 128/64 0
Gurupi 32/64 32/64 64/16 128/64 0
Ourem 8/16 32/16 >256/64 64/64 0
Caninde 32/64 64/64 64/16 128/64 0
Control 0 0 0 0 0
Results of plaque-reduction cross-neutralization tests with Changuinola group viruses performed at YARU were as follows [3] :
 
Virus Serum
CGL GUR Bt766 Bt2365 Bt104 OUR Bt2164 CoAr2837 IRI


0 = <2
CGL >256 0 >256 0 0 0 0 0 0
Gurupi 0 >256 0 4 0 8 0 0 0
Bt 766 >256 0 256 4 4 0 0 0 0
Bt 2365 0 0 0 64 0 0 128 2 0
Bt 104 0 0 0 0 32 0 0 0 0
Ourem 0 0 0 0 0 >256 0 0 0
Bt 2164 0 0 0 32 0 0 32 2 0
CoAr 2837 0 2 0 2 0 0 0 >256 0
Irituia 0 0 0 0 0 0 0 0 256
CGL = Changuinola; GUR = Gurupi; OUR = Ourem; IRI = Irituia
Results of neutralization tests performed in infant mice (ic route) at the Evandro Chagas Institute were as follows:
 
Virus Ascitic Fluid or Serum
IRI [5i] bGUR [5i] bOUR [4i] bCAN [5i] cJAM [5i] cALT [4i] c


b Ascitic fluid
c Serum
d LNI in dex
Irituia 3.0 d <1.0 0.8
Gurupi 2.5 <0.3 <0.3
Ourem 3.9 <1.0 <0.9
Ar 54342 3.0 0.8 0.4
Jamanxi 0.2 0.3 0 0.5 3.0 0
Altamira 1.1 1.2 1.0 1.0 0.9 >3.1
CAN = Caninde; JAM = Jamanxi; ALT = Altamira
 
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