CDC Home
CDC 24/7: Saving Lives. Protecting People.™

Centers for Disease Control and Prevention

CDC 24/7: Saving Lives. Protecting People.™

Centers for Disease Control and Prevention CDC 24/7: Saving Lives. Protecting People.™
ARBOVIRUS A-Z Index
  1. A
  2. B
  3. C
  4. D
  5. E
  6. F
  7. G
  8. H
  9. I
  10. J
  11. K
  12. L
  13. M
  14. N
  15. O
  16. P
  17. Q
  18. R
  19. S
  20. T
  21. U
  22. V
  23. W
  24. X
  25. Y
  26. Z

Arbovirus Catalog

Browse the Catalog

ArboCat Home


Virus Sections

Virus Name/Prototype
Original Source
Method of Isolation
Virus Properties
Antigenic Relationship
Biologic Characteristics
Natural Host Range
Susceptibility to...
Experimental Infection...
Histopathology
Human Disease
Geographic Distribution
References
Remarks

References

History
Abbreviations
Information Exchange

User Functions

Login to Contribute
Create an Account
Retrieve Password
 

  Hantaan   HTNV

Possible Arbovirus

No

3

Results of SALS surveys and information from the Catalogue.
Other Information
DOC Permit Required, USDA Restricted 

3
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
Hantaan virus has been tested against the following NIAID reagent polyvalent antisera by indirect fluorescent antibody (IFA) tests utilizing strain 76-118 infected A-549 cells as substrate. All sera were negative (<1:10) unless otherwise indicated. Group C (Lot 2); GMA gr.; SIM gr.; VSV gr.; BUN gr.; CALgr.; TCR gr.; PHL gr.; polyvalent QRF, KSO, QYB, polyvalent grs. ANA, ANB, TUR; polyvalent BWA, MOS, NDO; polyvalent PAT; CAP gr.; polyvalent PAL, COR, EUB; KEM gr.; polyvalent CON, NSD; polyvalents 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 12; polyvalent rabies, LCM, NDV, herpes, vaccinia; coronavirus (OC-43) and coronavirus (229E).
A weak atypical reaction was repeatedly observed at a 1:20 dilution of the Bunyamwera Group polyvalent MIAF. The following antisera prepared against individual BUN group viruses were tested by IFA with negative results (<1:10):
 


YARU Antisera CDC-Ft. Collins Antisera
BUN,BAT,ILE KRI,GRO,TAIASSUI GER,LOK,WYO,TEN,MAG,SAR SOR,ANH,NOR,CV,BIR,SHO
Of 161 monovalent HIAF raised against viruses of the Bunyaviridae, only the fluid to Anhembi virus reacted by IFA, at a titer of 16, to Hantaan virus [34] .
In addition, a polyvalent monkey anti Lassa-Machupo-Junin serum prepared at USAMRIID titered <10 as did anti-RVF rabbit serum and anti-Congo and anti- Hazara mouse serum. Direct conjugates of polyvalent group A (Alphaviruses) and polyvalent group B (Flavi) were also negative. Similarly, human convalescent sera from Machupo, Lassa, Marburg, and Ebola infections provided by Dr. Karl Johnson were negative when tested by IFA against strain 76-118 infected Apodemus lung sections.
The following virus complement-fixation (CF) antigens were tested by Dr. Robert Shope, YARU against two human KHF convalescent antisera. All CF tests were negative (<8). The human sera had Hantaan IFA titers of 320 and 640. AH, ACD, ACA, AKA, AMA, ANH, ANA, ANB, APEU, ARK, ARU, AMT, Abadina, BAN, BAK, BDA, BGN, BAU, BER, BHA, BLU, BOC, BTK, BUJ, BSB, BUT, BWA, BIA, AP, URU, BLM, CE, CDU, CAP, CHO, CHG, CHP, CGL, CHV, CNU, COC, CTF, CON, COR, COT, CR, Cedros, DEN-2, DGK, DHO, DUG, EEE, EHD, EUB, EgAn1398-61, Eret147, Farallon, FLA, GAM, GER, GA, GJA, GMA, GRO, GI, HAZ, HUA, HUG, ICO, IERI, ILE, IRI, ITP, ITQ, IbH11306, IbAn38918, Ichampadi, JOC, JAP, JOI, JUN, JUR, KK, KRI, KMP, KAN, KS, KAR, KEM, KC, KTR, KOO, KOW, KWA, KSO, KAM, KLA, kotonkan, LB, LJ, LJN, LEB, LD, LS, LUK, LCM, MAL, MAN, MAP, MCO, MTY, MAT, MEL, MNT, MIN, MIR, MOD, MOS, MEB, Mokola, NKO, NOLA, NYM, NDO, OKO, ORI, ORO, ORU, OLI, OYA, Obodhiang, PCA, PAC, PAL, PATA, PIC, PIRY, PT, QYB, QRF, Rabies, REO-3, SAL, SFN, SFS, SAT, SAW, SEM, SF, SIL, SIM, SOL, SLE, GF, TCM, TCR, TAM, TAT, TME, TEN, TETE, THI, THO, TPM, TNT, TUR, TSU, UMB, UPO, UUK, VEE, VSI, VSNJ, WM, WAL, WAN, WEE, WIT, WON, WYO, YATA, YF, YOG.
Hantaan virus was shown to be antigenically related to, but distinct from the recently registered Prospect Hill virus, rat isolates of Hantaan-like viruses and the agent of nephropathia epidemica [33] .
 
Download as PDF
<<<Click on the PDF icon to the left to view a copy of this virus entry in PDF format.
You can get a copy of the PDF viewer by clicking here.
 

Policies

Privacy

Contact Information

Centers for Disease Control and Prevention
1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636)
Contact CDC-INFO