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Virus Name: Hantaan

Abbreviation: HTNV

Status
Possible Arbovirus

Select Agent
No

SALS Level
3

SALS Basis
Results of SALS surveys and information from the Catalogue.

Other Information
DOC Permit Required, USDA Restricted

Antigenic Group
3

Section VII - Natural Host Range (Additional text can be added below table)

Vertebrate (species and organ) and arthropod	No. isolations/No. tested	No. with antibody/No. tested Test used	Country and region


^* Clinically severe cases. Inapparent infection rates, as indicated by significant levels of KHF antibody, range from 2.7% to 4% in long term residents of endemic areas to less than 1% in short term residents of endemic areas or long term residents of non-endemic areas.
^** Patients with febrile illnesses of unknown origin (1035), or blood donors (664). Only 1 of 13 positive humans had both IFA and NT antibodies to Hantaan virus.
NOTE: It has not been established whether the Suncus murinus isolate is identical to Hantaan virus or to Seoul virus (prototype of rat isolates).

Man (blood)	6/66	113/116 ^* IFA	South Korea; Seoul N. to 28 parallel (1)
Apodemus agrarius coreae (lung, kidney)	114/817		South Korea; along the Hantaan river near the 38th parallel; N.(1)
Apodemus agrarius jejuensis	0/238
Microtus fortis pelliceus	0/103
Crocidura lasiura	0/71
Clethrionomys rufocanus regulus	0/35
Cricetulus triton nestor	0/9
Mus musculus yamashinai	0/17
Tamias sibiricus asiaticus	0/1
Man		7/542 IFA	North Greece (22), China (35, 40)
Suncus murinus (insectivore)	1/2
Humans	7/1035 ^**		NC;CO, USA (39)
Humans		6/664 ^** IFA	WV;MD, USA (39)

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