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Virus Name: Hughes

Abbreviation: HUGV

Status
Probable Arbovirus

Select Agent
No

SALS Level
2

SALS Basis
Results of SALS surveys and information from the Catalogue.

Other Information

Antigenic Group
Hughes

Section VIII - Susceptibility to Experimental Infection (include viremia)

Experimental host and age	Passage history and strain	Inoculation Route-Dose	Evidence of infection	AST (days)	Titer log10/ml


Mice (nb)	P-2	ic .02	Paralysis and death	5-7
Mice (nb)	P-4	ip 0.1	Paralysis and death	5-7	4.25
Mice (nb)		sc
Mice (wn)		ic .03	Tremors convulsions	8-10	3.75
Mice (wn)		ip	Antibody
Mice (nb)	P-24	ic .02	Paralysis and death	6	5.15
Mice (nb)	P-41	ic .02	Death	5-6	6.15
house mice(10 day)	P-4	ic and ip .02	Paralysis and death	9-10
house mice (ad)		ic .03	Paralysis and death	11	4.75
hamsters (9 day)	P-3	ic .05	Paralysis and death	9
hamsters (ad)		ip .25	Antibody
Peromyscus sp.(ad) P-9		ic .03	None	9
guinea pigs (yg)	P-1, P-3	ic 0.25	Tremors, temp. and convulsions
rhesus monkey (ad)	P-4	ic	6 days fever after 14 day incubation period


embryonated eggs (6 day)		ys 0.25	Death	5-6
chicks (1-2 day)		ic .02	Paralysis and death	5-8
chicks (1-2 day		ip 0.1	None, no antibody prod.
sooty terns (juv.) (caught wild)	P-5	sc 0.1	Viremia (8)		<3.40

noddy terns (juv.) (caught wild)		sc 0.1	Viermia (8)		<3.40

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