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  Issyk-Kul   IKV

Arbovirus

No

3

Isufficient experience with virus; i.e., experience factor from SALS surveys was less than 500 in laboratory facilities with low biocontainment.
Other Information
 

Ungrouped
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
Issyk-Kul antigen in the CF test did not react with poly-antisera to arbovirus groups A, B, C. It did not react with antisera to: arboviruses Simbu, Akabane, Sabo, Samford, Sango, Shamonda, Sathuperi in the Simbu group; Uukuniemi, Grand Arbaud, Manawa, Zaliv Terpeniya in the Uukuniemi group; California, Tahyna, Kaspiy in the California group; Qalyub, Bandia in the Qalyub group; Kaisodi, Silverwater, Lanjan in the Kaisodi group; Japanese encephalitis, tick-borne encephalitis, Tyuleniy, Sokuluk in group B; Bakau, Ketapang in the Bakau group; Palyam in the Palyam group; Quaranfil in the Quaranfil group; SF Sicilian, SF Naples, Candiru, Bujaru, Chagres in the SF group; Bunyamwera, Batai in the Bunyamwera group; Chandipura in the VSV group; Hughes in the Hughes group; Kemerovo, Wad Medani, Baku, Okhotskiy in the Kemerovo group; and various other viruses such as Dhori, Upolu, Matucare, Lone Star, DGK, KHF, Bhanja, CTF, Lagos bat, Ogunpa, Nyamanini, Jos, Wanowrie, Sawgrass, LEIV-65A, LEIV-1308 Uz, LEIV-858 Uz, LEIV-1682 Tu, Dugbe, IbAr 2012. Ectromelia, reovirus 3, EMC, lymphocytic choriomeningitis and rabies were serologically excluded.
Issyk-Kul and Keterah viruses have been shown to be closely related or identical by complement-fixation [5] . Cross-neutralization testing will determine whether they are the same virus or antigenic relatives. Pending the results of that testing, these viruses are being listed in the ungrouped category (Ed.).
 
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