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Virus Name: Itimirim

Abbreviation: ITIV

Status
Possible Arbovirus

Select Agent
No

SALS Level
3

SALS Basis
Isufficient experience with virus; i.e., experience factor from SALS surveys was less than 500 in laboratory facilities with low biocontainment.

Other Information

Antigenic Group
Guama

Section V - Antigenic Relationship and Lack of Relationship to Other Viruses

Complement-fixation tests showed that Itimirim virus was closely related to Guaratuba virus and slightly less so to Bertioga and Mirim viruses, all members of the Guama serogroup.

Results of serum dilution-plaque reduction neutralization tests, in Vero cells, with seven Guama serogroup viruses, Guaratuba, Mirim, and Minatitlan viruses and four isolates from Brazil.

Titer ^* of Antibody to:
Virus	Strain	SPAn 47817	SPAn 64706	SPAn 64962	76V- 25643	BER	GTB	MIR


Itimirim	SPAn 47817	>1280	0	0	0	0	0	40
	SPAn 64706	0	640	0	0	0	320	0
Cananeia	SPAn 64962	0	0	640	0	0	0	0
	76V-25643	0	0	0	640	320	0	0
Bertioga	SPAn 1098	0	0	0	640	320	0	0
Guaratuba	SPAn 12252	0	>1280	0	0	0	320	0
Mirim	BeAn 7722	0	0	0	0	0	0	320
Guama	BeAn 277	0	0	0	0	0	0	0
Bimiti	TR 8362	0	0	0	40	0	0	0
Moju	BeAr 12590	0	0	0	0	0	0	0
Catu	BeH 151	0	0	0	0	0	0	0
Mahog. Ham	Fe4-2S	0	0	0	0	0	40	0
Ananindeua	BeAn 109303	0	0	0	0	0	0	0
Minatitlan	M67U5	0	0	0	0	0	0	0

Titer ^* of Antibody to:
Virus	Strain	GMA	BIM	MOJU	CATU	MH	ANU	MNT


^* Reciprocal of highest dilution producing >90% reduction; 0 = <40.
Itimirim	SPAn 47817	0	0	40	0	0	0	0
	SPAn 64706	0	0	0	0	0	0	0
Cananeia	SPAn 64962	0	0	0	0	0	0	0
	76V-25643	0	0	40	0	0	0	0
Bertioga	SPAn 1098	0	0	0	0	0	0	0
Guaratuba	SPAn 12252	0	0	0	0	0	0	0
Mirim	BeAn 7722	0	0	0	0	0	0	0
Guama	BeAn 277	>1280	0	0	0	0	0	0
Bimiti	TR 8362	0	>1280	0	0	0	0	0
Moju	BeAr 12590	0	0	320	0	0	0	0
Catu	BeH 151	0	0	40	640	0	0	0
Mahog. Ham.	Fe4-2S	160	0	40	0	>1280	0	0
Ananindeua	BeAn 109303	160	0	0	0	0	80	0
Minatitlan	M67U5	0	0	0	0	0	0	>1280

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