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| A CF screening test using a 1/10 dilution of MP 6186 antigen was performed against hyperimmune mouse antisera to the following arboviruses: |
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|
| | chikungunya | Bwamba | | Middelburg | Simbu | | Sindbis | Nyando | | West Nile | Mossuril | | yellow fever | Witwatersrand | | Zika | Congo (Semunya) | | Bunyamwera |
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| MP 6186 was also tested against reagents to 75 African arboviruses and broad group mouse ascitic fluids for arbovirus groups A, B, C, Guama, and California. All results were negative except with Mossuril. Cross CF and neutralization tests with Mossuril gave the following results: |
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| | | | Neutralization Test |
|---|
| | CF Antigens | | | Viruses |
|---|
| Antiserum | Kamese | Mossuril | | Antiserum | Kamese | Mossuril |
|---|
|
| | * Antiserum titer/antigen titer | | ** LNI expressed in dex | | Kamese | 160/40 * | 80/40 | | Kamese | > 3.5 ** | 1.7 | | Mossuril | 40/40 | 40/40 | | Mossuril | 0.5 | > 3.0 |
|
| Results indicate that MP 6186 is a hitherto undescribed virus strain related to Mossuril. |
| Hart Park, Flanders, Mosqueiro, Mossuril and Kamese viruses cross-reacted by IFA, CF and NT and by EIA [5] . They form the Hart Park antigenic group. |
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