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  Kasba   KASV

Possible Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
 

Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
By CF G15534 antigen did not react with (homologous titer in parenthesis) hyperimmune sera against Sindbis (256), chikungunya (256), Japanese encephalitis (512), West Nile (256), dengue 2 (256), Kyasanur Forest disease (256), Venkatapuram (128), Ganjam (256), Umbre (>64), Sathuperi (16), Minnal (32), Kaisodi (64), Arkonam (128), Wanowrie (128), Wad Medani (256), Bhanja (256), Batai (256), bluetongue (128), AHS (>64), HEV (256), Chandipura (>64), Blalgodu (>64).
CF tests carried out by Dr. R.E. Shope at YARU indicated that there was no reaction with immune ascitic fluids against Colorado tick fever, Eubenangee, Corriparta, Kemerovo, Chenuda, Wad Medani, Tribec, Lebombo, EHD and Changuinola.
Related by CF to Palyam (G5287) and Vellore (68886) viruses but distinct by neutralization test.
Antigenic relationship among Palyam, Kasba and Vellore viruses.
 
Immune Sera
Palyam Kasba Vellore
Antigen CF NT CF NT CF NT


a Serum titre/antigen titre
b Log neutralization index in dex
Palyam 256/64 a >2.7 b 256/32 0.9 128/64 0.6
Kasba 128/16 1.4 256/64 >4.0 128/64 1.2
Vellore 128/16 0.7 128/32 1.0 128/64 >2.7
Another virus, B8112 from Australia, has been found to be related to these viruses by CF test; neutralization tests indicate that virus B8112 was related but not identical to Vellore virus (information from Dr. Shope).
 
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