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  Kotonkan   KOTV

Probable Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
 

rabies serogroup
Section IX - Experimental Arthropod Infection and Transmission
 
 
Arthropod species & virus source(a) Method of Infection log10/ml (b) Incubation period (c) Transmision by bite (d) Assay of arthropod, log10/ml (e)
Feeding Injected Days °C Host Ratio Whole Organ System


Ae. aegypti, An quadrimaculatus, Cx quinquefasciatus, Er chrysogaster, 30 ea., innoc. with 10% mouse brain kotokan virus (IbAr 23380), P-8, titer 5.4 dex LD50/ml., 0.0006 ml/mosq. Every 14 days 5 paris sal. glands (1 ml dil.) passed to 30 clean mosqs. and inoc. ic baby mice; virus confirmed by CF. Kotokan pass. 5 times Ae and virus recovered to 72 days, An 4 times to 58 days, Cx 2 times to 30 days, Er 16 days. Mosq. virus not transmitted by bite to baby mice infect. sc with sal. gland virus. Low level viremia baby mice 3-5 days pi (ic) (8).
 
 
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