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  Minatitlan   MNTV

Possible Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
 

Minatitlan
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
159 antigens in the YARU collection were tested by CF test against an M67U5 mouse ascitic fluid [2] with lack of cross-reaction. The only positive reaction at 1:4 or greater was with the homologous antigen, the ascitic fluid titer being 1024.
In addition, the M67U5 antigen was tested by CF with hyperimmune ascitic fluids of groups A, B, C, Guama, Capim, California, Simbu, Bunyamwera, Anopheles A, Anopheles B, Turlock, Phlebotomus fever, Quaranfil, Kaisodi, Lanjan, VSV, Tacaribe, and ascitic fluids of herpes simplex, vaccinia, LCM, NDV, rabies, ectromelia, reovirus 3, and Rift Valley fever.
HI and N testing has been done but not as completely as by CF tests.
M67U5 virus antigen gave a titer of 20 only against a group C polyvalent ascitic fluid. This test was performed twice in two different laboratories (Instituto Nacional de Virologia and Cornel University Medical College).
These data indicate that M67U5 is a new virus, belonging in the Bunyamwera supergroup, but not pertaining to any of the established groups within the supergroup.
More recent data indicate that Minatitlan virus is closely related by CF and NT to Palestina virus, which was registered in 1982 [5] . Therefore, the two viruses comprised the Minatitlan serogroup.
Cross-reactivity of Palestina and Minatitlan and Mirim viruses by CF and serum dilution-plaque reduction neutralization tests.
 
MIAF
CF NT
Antigen or Virus 76V-1565 MNT MIR 76V-1565 MNT MIR


NT titer: reciprocal of highest dilution producing >90% plaque-reduction.
Palestina 64 128 8 160 <20 <20
Minatitlan 16 256 8 40 2560 <20
Mirim 8 8 256 <20 <20 320
 
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