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Virus Name:
Nairobi sheep disease
Abbreviation:
NSDV
Status
Arbovirus
Select Agent
No
SALS Level
SALS Basis
Other Information
USDA Permit Required, USDA Restricted
Antigenic Group
Nairobi Sheep Disease
Remarks
The disease is one with a high morbidity and often a catastrophically high mortality in sheep, more than 75% of a flock being lost. A modified strain of the agent has been produced by Weinbren and Gourlay which induces only a mild thermal reaction when introduced into a susceptible sheep but which confers lasting and solid immunity as demonstrated by challenge with large doses of autochthonous virus. R. appendiculatus is the usual vector. Daubney and Hudson claim occasional transmission with A. variegatum but Hoogstraal doubts accuracy of identification. Weinbren and Gourlay have made many unsuccessful transmission attempts with Ae aegypti. Lewis achieved transmission with R. appendiculatus 871 days after infection.
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