| | | | | Vertebrate (species and organ) and arthropod | No. isolations/No. tested | No. with antibody/No. tested Test used | Country and region |
|---|
|
| | Other isolations: laboratory rat, 1 Japan (25); laboratory rat tumor, 1 Japan (26); Rattus nitidus 1 China (27); Bandicota indica, 1 Thailand (24). Other Rattus spp. isolates have been obtained in Brazil, Thailand and the United States. It has not been established that the bandicoot rat isolate is identical to other rat isolates or to Hantaan virus. | | 4/1,788 humans had IFA, ELISA and NT antibodies; neutralizing antibody titrations indicated that infections were caused by a rat-associated virus(30). | | * Clinically severe and moderate hospitalized cases in Seoul City where only urban rats were found. The patients have never been in rural endemic areas of HFRS for two months prior to illness. Inapparent infection rates, as indicated by significant levels of IF antibody, are 1% among urban residents of Seoul and 10% among urban residents of Incheon. Many cases of HFRS occurred among urban residents of Osaka and several outbreaks of HFRS occurred in animal rooms of medical centers in Japan (12-17). | | 4/1,788 humans had IFA, ELISA and NT antibodies; neutralizing antibody titrations indicated that infections were caused by a rat-associated virus(29). | | | | Rattus norvegicus (lungs) | 37/477 | 63/477 IFA | Seoul and 4 nearby cities, Korea | | Rattus rattus (lungs) | 2/47 | 5/47 IFA | | | Rattus norvegicus (lungs) | 2/208 | 64/208 IFA | Tokyo bay area, Japan | | Rattus norvegicus | 1 | | New Orleans, Louisiana USA (23) | | Rattus norvegicus | 1 | | Philadelphia, Pennsylvania, USA(28) | | Rattus norvegicus | 1 | | Houston, Texas USA(28) | | Sprague-Dawley rats (lungs) | 2/501 | 208/501 IFA | Seoul, Korea | | Wistar rats (lungs) | 1/480 | 165/480 IFA | | | Wild rats | | 112/1,262 IFA | Various states USA(23) | | Man (blood) | Not tested | 293/356 * IFA | Seoul, Korea; 1980-84 | | Man (blood) | Not tested | 19/20 IFA | Osaka, Japan |
| | |
|
