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  Sixgun City   SCV

Possible Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
 

Kemerovo
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
 
Sixgun City Antigen/Virus
CF SMNT
Immune Sera Ht/Ho Ratio Ht/Ho


Mono Lake (Ar 861) 32/64 1/2 3.5/6.0(a)
Huacho (Ar 883) 16/32 1/2 1.9/4.5
Chenuda (Ar 1170) 0/128 0/128 -
 
Sixgun City Immune Serum
CF SMNT
Antigens/Viruses Ht/Ho Ratio Ht/Ho


a LNI in dex
Mono Lake (Ar 861) 64/64 1 6.0/3.7 a
Huacho (Ar 883) 16/32 1/2 2.9/3.7
Chenuda (Ar 1170) 0/128 0/128 -
In a tissue-culture neutralization test, Sixgun City virus plaques were unaffected by immune sera from 13 viruses: Chenuda (Ar 1170), Nyamanini (Ar 1304), Sapphire I, Sapphire II, Johnston Atoll, Powassan (791A), Quaranfil (Ar 1113), Raza, Matucare, Midway (RML 47153), Wad Medani (Ar 492) and Punta Salinas (Ar 888). However, Sixgun City virus plaques were significantly neutralized (>3.0 dex) upon exposure to Mono Lake (Ar 861) and Huacho (Ar 883) immune sera [1] . In CF tests we were unable to show a relationship between Sixgun City and Chenuda viruses, although this was readily demonstrated for Mono Lake and Chenuda viruses [1] . Further work may reveal Mono Lake, Huacho and Sixgun City viruses to be geographic or populational variants of a single virus.
 
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