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Virus Name: Tehran

Abbreviation: TEHV

Status
Possible Arbovirus

Select Agent
No

SALS Level
2

SALS Basis
Placed at this biosafety level based on close antigenic or genetic relationship to other viruses in a group of 3 or more viruses, all of which are classified at this level.

Other Information

Antigenic Group
Phlebotomus Fever

Section V - Antigenic Relationship and Lack of Relationship to Other Viruses

Results of HI test [2] .

	Antisera to:
Antigens	Karimabad	Tehran	Naples	Sicilian	Salehabad


^a HI titers with 8 HA units of antigen; 0 = <1:20
Karimabad	640 ^a	0	40	0	80
Tehran	640	320	640	0	80
Naples	640	160	1280	0	20
Sicilian	40	0	0	1280	0
Salehabad	320	0	20	0	320

Results of CF and plaque-reduction neutralization tests (PRNT) [4] .

	CF			PRNT
	Antibody to:			Antibody to:
Antigen/Virus	Naples	ISS.Phl.3	Tehran	Naples	ISS.Phl.3	Tehran


^b Highest serum titer/highest antigen titer
^c Reciprocal of highest serum dilution giving >90% plaque reduction.
Naples	256/128 ^b	64/64	128/128	320 ^c	10	<10
ISS.Phl.3	128/256	256/> 512	128/256	20	> 5120	<10
Tehran	128/64	64/64	256/128	<10	<10	80

In cross-neut. tests, Tehran virus and immune serum did not react with: AGU, ALE, ANH, AMT, BUE, BUJ, CAC, CAI, CDU, CHG, CHI, FRI, GF, GOR, ICO, ITA, ITP, KAR, NIQ, PAC, PT, RVF, RG, SAF, SAL, SFS, TRA, or URU viruses or immune sera [4] .

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