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  Thimiri   THIV

Possible Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
Other Information
 

Simbu
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
In complement-fixation tests performed in Vellore, non-reactive with hyperimmune mouse sera to: group A virus, Sindbis; group B viruses, dengue, Japanese, encephalitis, West Nile; other arboviruses including Chittoor (Bunyamwera), Sathuperi (Simbu) and Umbre (Turlock); other agents isolated previously in Vellore and believed to be arboviruses though not at the time identified or grouped; and to the LGV- ornithosis viruses. Reactive with hyperimmune mouse sera to other strains of same agent.
At the Yale Arbovirus Research Unit (YARU), the Thimiri virus (I66414) was found to be closely related or identical by CF and NT to viruses isolated in Egypt from a Sylvia communis in 1963 (EgAn 6165) and from a Sylvia curraca in 1966 (EgAn 890-3). The EgAn 890-3 strain reacted by CF with Simbu grouping ascitic fluid and not with 16 other grouping fluids. A Serum of EgAn 890-3 with homologous titer of 1024 reacted to 16 with Buttonwillow, to 32 with Oropouche and to 8 with Simbu antigens and was negative with 6 others, indicating that the relationship by CF to the Simbu group viruses was definite [4] .
Results of cross-neutralization comparisons of Simbu group viruses place Thimiri virus in the Thimiri complex within the Simbu serogroup [6] .
 
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