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Virus Name:
Tonate
Abbreviation:
TONV
Status
Probable Arbovirus
Select Agent
No
SALS Level
3
SALS Basis
Isufficient experience with virus; i.e., experience factor from SALS surveys was less than 500 in laboratory facilities with low biocontainment.
Other Information
USDA Permit Required, Hepa Filtration, Vaccination Recommended
Antigenic Group
A
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
CF test - homologous titer = 256/16. Institut Pasteur Cayenne:
CaAn 410d gives positive results with viruses of VEE complex [2] .
Complement-fixation test:
Antigens
Tonate
Mucambo
Pixuna
Cabassou
VEE ID
VEE IE
Everglades
Asciticfluid
CaAn 410d
BeAn 8007
BeAr 35645
CaAr 508
3880
Mena II
Fe 37 C
a
Maximum titer of antiserum/optimum titer of antigen
Tonate
256/16
a
16/16
<8/<8
16/32
16/32
16/64
16/64
Mucambo
32/16
128/16
Pixuna
<8/<8
64/64
Cabassou
64/16
64/64
VEE ID
<8/<8
16/128
VEE IE
<8/<8
16/64
Everglades
64/16
256/64
Neutralization test:
Virus
Tonate
Mucambo
Ascitic fluid
CaAn 410d
BeAn 8007
b
LNI in dex
Tonate
5.5
b
3.5
Mucambo
1.5
5.2
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