Prevention Research Synthesis
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PRS Compendium Featured Interventions

This feature focuses on interventions for persons who are out of, or inconsistent in, HIV care.
Cooperative Re-engagement Controlled Trial (CoRECT): Connecticut
PubMed record
Linking and Retention Evidence-Based Intervention

Intended population: People with HIV (PWH) who are newly out of care

Intervention effects/outcomes: Improved re-engagement in HIV care

Study years: 2016 – 2018

Structural components: Access, Policy/Procedure, Social Determinants of Health


Fanfair, R. N., Khalil, G., Williams, T., Brady, K., DeMaria, A., Villanueva, M., Randall, L. M., Jenkins, H ., Altice, F. L., Camp, N., Lucas, C., Buchelli, M., Samandari, T., & Weidle, P. J. (2021). The Cooperative Re-Engagement Controlled Trial (CoRECT): A randomised trial to assess a collaborative data to care model to improve HIV care continuum outcomes. Lancet Regional Health-Americas, 3, 100057. https://doi.org/10.1016/j.lana.2021.100057

ACCESS NY Patient Navigation Program
PubMed record
Structural Evidence-Based Intervention

Intended population: People with HIV enrolled in the Amida Care health plan who were never in care or lost to care

Intervention effects/outcomes: Increased engagement and re-engagement in HIV care

Study years: 2010 – 2013

Structural components: Access, Capacity Building, Policy/Procedure, Social Determinants of Health


Messeri, P., Yomogida, M., Ferat, R. M., Garr, L., & Wirth, D. (2020). An HIV health plan patient navigation program: Engaging HIV positive individuals in primary medical care. Journal of HIV/AIDS & Social Services, 19(1), 55-73.

HIV Care Coordination Program (CCP)
PubMed record
Linking and Retention Evidence-Based Intervention

Intended population: Persons with HIV (PWH) who are newly diagnosed, new to HIV care, out of HIV care, new to HIV treatment, undergoing a change in treatment regimen, virally unsuppressed at their most recent viral load test, experiencing co-occurring conditions, or at high risk of being lost to care or not achieving viral suppression due to psychosocial or structural barriers to engagement in HIV care and treatment

Intervention effects/outcomes: Increased viral suppression

Study years: 2009 – 2017

Structural components: Access, Physical Structure


Robertson, M. M., Penrose, K., Nash, D., Harriman, G., Braunstein, S. L., Levin, B., & Irvine, M. K. (2020). Impact of an HIV care coordination program on the timeliness of viral suppression and immune recovery among clients newly diagnosed with HIV. AIDS and Behavior, 24(4), 1237-1242.

LINCS (Linkage, Integration, Navigation, and Comprehensive Services)
PubMed record
Structural Evidence-Informed Intervention

Intended population: People with HIV (PWH) who are not in care (NIC)

Intervention effects/outcomes: Increased retention in HIV care, Increased viral suppression

Study years: 2015 – 2017

Structural components: Access, Capacity Building, Policy/Procedure


Sachdev, D. D., Mara, E., Hughes, A. J., Antunez, E., Kohn, R., Cohen, S., & Scheer, S. (2020). “Is a bird in the hand worth 5 in the bush?”: A comparison of 3 data-to-care referral strategies on HIV care continuum outcomes in San Francisco. Open Forum Infectious Diseases, 7(9), ofaa369. doi: 10.1093/ofid/ofaa369.