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PRS Compendium Featured Interventions

September 27 is National Gay Men’s HIV/AIDS Awareness Day. This feature focuses on the newest interventions for men who have sex with men (MSM).

M-Cubed (Mobile Messaging for Men)

PubMed record

Risk Reduction Evidence-Based Intervention (Best)

Intended population: Gay, bisexual, and other men who have sex with men (GBMSM)

Intervention effects/outcomes: Increased HIV testing, Increased PrEP

Study years: 2018 – 2019

Structural components: None reported

Sullivan, P. S., Stephenson, R., Hirshfield, S., Mehta, C. C., Zahn, R., Bauermeister, J. A., Horvath, K., Chiasson, M. A., Gelaude, D., Mullin, S., Downing, M. J., Olansky, E. J., Wiatrek, S., Rogers, E. Q., Rosenberg, E., Siegler, A. J., & Mansergh, G. (2022). Behavioral efficacy of a sexual health mobile app for men who have sex with men: Randomized controlled trial of Mobile Messaging for Men. Journal of Medical Internet Research, 24(2), e34574. doi: 10.2196/34574

Navigation for PrEP Persistence

PubMed record

Pre-Exposure Prophylaxis Evidence-Informed Intervention

Intended population: Black or African American men who have sex with men (MSM)

Intervention effects/outcomes: Improved PrEP initiation/uptake

Study years: 2018 – 2022

Structural components: None reported

Goedel, W. C., Coats, C. S., Chan, P. A., Sims-Gomillia, C. E., Brock, J. B., Ward, L. M., Mena, L. A., & Nunn, A. S. (2022). A pilot study of a patient navigation intervention to improve HIV pre-exposure prophylaxis persistence among Black/African American men who have sex with men. JAIDS Journal of Acquired Immune Deficiency Syndromes, 90(3), 276–282. doi.org/10.1097/QAI.0000000000002954

SMART Sex Ed

PubMed record

Pre-Exposure Prophylaxis Evidence-Informed Intervention

Intended population: English and Spanish speaking adolescent men who have sex with men (AMSM), who are 13-18 years old and do not have HIV

Intervention effects/outcomes: Increased PrEP use

Study years: 2018 – 2020

Structural components: None reported

Mustanski, B., Saber, R., Macapagal, K., Matson, M., Laber, E., Rodriguez-Diaz, C., Moran, K. O., Carrion, A., Moskowitz, D. A., & Newcomb, M. E. (2022). Effectiveness of the SMART Sex Ed program among 13-18 year old English and Spanish speaking adolescent men who have sex with men. AIDS and Behavior, 27(2), 733-744. doi: 10.1007/s10461-022-03806-2

Stronger Together

PubMed record

Medication Adherence Evidence-Based Intervention (Good)

Intended population: Cisgender male HIV serodiscordant couples

Intervention effects/outcomes: Improved ART prescription and use, Improved ART adherence

Study years: 2014 – 2017

Structural components: Capacity Building

Stephenson, R., Garofalo, R., Sullivan, P. S., Hidalgo, M. A., Bazzi, A. R., Hoehnle, S., Bratcher, A., Finneran, C. A., & Mimiaga, M. J. (2021). Stronger Together: Results from a randomized controlled efficacy trial of a dyadic intervention to improve engagement in HIV care among serodiscordant male couples in three US cities. AIDS and Behavior, 25(8), 2369-2381. doi: 10.1007/s10461-021-03199-8

TRUST

PubMed record

Structural Evidence-Based Intervention

Intended population: Young Black or African American men who have sex with men (YBMSM) and transgender women (TW)

Intervention effects/outcomes: Increased HIV self-testing

Study years: 2016 – 2017

Structural components: Access, Physical Structure

Frye, V., Nandi, V., Paige, M. Q., McCrossin, J., Lucy, D., Gwadz, M., Sullivan, P., Hoover, D., Wilton, L., & TRUST Study Team. (2021). TRUST: Assessing the efficacy of an intervention to increase HIV self-testing among young Black men who have sex with men (MSM) and transwomen. AIDS and Behavior, 25(4), 1219-1235. doi: 10.1007/s10461-020-03091-x