Prevention Research Synthesis
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Pre-Exposure Prophylaxis Evidence-Informed Intervention

Target population: High-risk HIV-negative young black men who have sex with men (YBMSM)

Intervention effects/outcomes: Improved PrEP initiation/uptake

Study years: 2016 – 2017


Desrosiers, A., Levy, M., Dright, A., Zumer, M., Jallah, N., Kuo, I., Magnus, M., & Siegel, M. (2019). A randomized controlled pilot study of a culturally tailored counseling intervention to increase uptake of HIV pre-exposure prophylaxis among young black men who have sex with men in Washington, DC. AIDS and Behavior, 23, 105–115.

Pre-Exposure Prophylaxis Evidence-Based Intervention

Target population: HIV-negative young men who have sex with men (YMSM) at risk for HIV acquisition

Intervention effects/outcomes: Improved retention in PrEP care; Improved PrEP medication adherence/persistence

Study years: 2015 – 2016


Liu, A. Y., Vittinghoff, E., von Felten, P., Amico, K. R., Anderson, P. L., Lester, R., Andrew, E., Estes, I., Serrano, P., Brothers, J., Buchbinder, S., Hosek, S., & Fuchs, J. D. (2019). Randomized controlled trial of a mobile health intervention to promote retention and adherence to preexposure prophylaxis among young people at risk for human immunodeficiency virus: The EPIC Study. Clinical Infectious Diseases, 68(12): 2010-2017.

Pre-Exposure Prophylaxis Evidence-Informed Intervention

Target population: Men who have sex with men (MSM) who are HIV-uninfected and at high risk for HIV acquisition

Intervention effects/outcomes: Increased PrEP adherence/persistence

Study years: 2012 – 2014


Mayer, K. H., Safren, S. A., Elsesser, S. A., Psaros, C., Tinsley, J. P., Marzinke, M., Clarke, W., Hendrix, C., Wade Taylor, S., Haberer, J., & Mimiaga, M. J. (2017). Optimizing pre-exposure antiretroviral prophylaxis adherence in men who have sex with men: Results of a pilot randomized controlled trial of “Life-Steps for PrEP.” AIDS and Behavior, 21, 1350-1360.