Table of Contents

Component Description

IgG autoantibody testing of a subsample of stored serum from 1999-2004 participants was conducted to estimate the prevalence and specificities of selected autoantibodies in the US population.

Eligible Sample

One third subsample of participants aged 12 years and older from 1999-2004.

Description of Laboratory Methodology

Immunofluorescence analysis
Testing of IgG autoantibodies to human cellular antigens was performed by the HEp-2 cell immunofluorescence assay using slides from INOVA Diagnostics, San Diego, CA (Cat # 508100) following the manufacturer’s instructions and evaluated primarily using their NOVA View system. The cellular pattern of staining and staining intensity from 0 to 4+ was described using a reference gallery per below and description of patterns are consistent with those described by the International Consensus on ANA Pattern (ICAP) committee [ref. Chan EKL, Damoiseaux J, Carballo OG, Conrad K, de Melo Cruvinel W, Francescantonio PL, Fritzler MJ, Garcia-De La Torre I, Herold M, Mimori T, Satoh M, von Muhlen CA, Andrade LE. Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014-2015. Front Immunol. 2015;6:412. PMC:4542633]. The determination of autoantibody titers from 1:80 to 1:1280 was performed by serial dilution on samples that showed a 3+ or greater nuclear and/or cytoplasmic immunofluorescence pattern.

Laboratory Quality Assurance and Monitoring

Immunofluorescence analysis
Serum samples were tested using established protocols outlined by manufacturer. A set of CDC autoimmune reference sera (12 different specificities) (Chan EKL et al., 2007) and 2 healthy control sera were coded and tested in a blinded fashion two times to verify consistent results throughout screening tests: towards the beginning and when approximately half of the samples were tested.

Samples that showed discrepant results were repeated. Repeats were performed whenever there was any doubt for accuracy or technical issues.

Data Processing and Editing

Data Access: All data are publicly available.

Analytic Notes

The NHANES Survey Design:

The analysis of NHANES laboratory data should be conducted using the key survey design variables. The NHANES Demographic data files for each 2-year survey cycle contain core information on the survey and the survey design variables for strata and PSU (SDMVSTRA and SDMVPSU, respectively) which are recommended to be used in variance estimation. This laboratory data files may be linked to other NHANES data files using the unique survey participant identifier SEQN.

Weighting:

Special subsample sample weights WTANA6YR in the file are required to analyze the NHANES 1999-2004 ANA data. This is because the ANA data were analyzed using stored serum samples obtained from survey participants who had been selected from NHANES 1999-2004 Dioxin subsamples. The NHANES 1999-2004 ANA sample and the subsample weights were created for 6 years analysis and should be used to analyze all six years together.

 

Immunofluorescence analysis 

A standard gallery of images showing the intensity of staining and the cellular patterns of reactivity is shown below and the following patterns were reported:

Nuclear patterns
1) homogeneous (AC-1); 2) dense fine speckled (AC-2); 3) centromere (AC-3); 4) fine speckled (AC-4); 5) Coarse speckled (AC-5); 6) nuclear dots (AC-6/AC-7); 7) nucleolar (AC-8/AC-9/AC-10); 8) nuclear envelope (AC-11/AC-12); 9) PCNA-like (AC-13); 10) CENP-F-like (AC-14)

Cytoplasmic patterns
1) cytofilament (AC-15/AC-16/AC-17); 2) GW Body (AC-18); 3) homogeneous (AC-19); 4) speckled (AC-20); 5) mitochondria-like (AC-21); 6) Golgi complex (AC-22); 7) rods/rings (AC-23)

Mitotic cell patterns
1) centrosome (AC-24); 2) spindle apparatus (AC-25); 3) NuMA-like (AC-26); 4) mid-body (AC-27); 5) mitotic chromosomal (AC-28)

Nuclear staining

Images

Description of staining patterns

Homogeneous (AC-1)

https://www.anapatterns.org/imgNew/prontas/1473302132-0.jpg?1532830286

Homogeneous and regular fluorescence across all nucleoplasm

Nuclear dense fine speckled (AC-2)

https://www.anapatterns.org/imgNew/prontas/1473302361-0.jpg?1532830487

Speckled pattern distributed throughout the interphase nucleus with characteristic heterogeneity in the size, brightness and distribution of the speckles. The metaphase plate depicts strong speckled pattern with some coarse speckles standing out.

Centromere (AC-3)

Discrete speckles (40-80/cell) in interphase cells and on metaphase plates

Discrete coarse speckles (40-80/cell) scattered in interphase cells and aligned at the chromatin mass on mitotic cells

Nuclear fine Speckled (AC-4)

Fine tiny speckles across all nucleoplasm

Nuclear coarse speckled (AC-5)

Coarse speckles across all nucleoplasm.

Nuclear dots (AC-6/AC-7)

Countable discrete speckles PML bodies, Cajal bodies (coiled bodies)

Countable discrete speckles PML bodies, Cajal bodies (coiled bodies)

Nucleolar (AC-8/AC-9/AC-10)

Homogeneous or speckled staining of the nucleolus

Homogeneous or speckled staining of the nucleolus

Nuclear envelope (AC-11/AC-12)

 Homogeneous nuclear staining with greater intensity at its outer rim

Homogeneous nuclear staining with greater intensity at its outer rim

PCNA-like (AC-13)

Pleomorphic speckled nucleoplasmic staining, with variability in size and brightness of the speckles. In interphase, some cells are negative (G1 phase), some are intensely stained (S-phase) and some present rare and scattered speckles with occasional nucleolar staining.

CENP-F-like (AC-14)

Nuclear speckled pattern with striking variability in intensity with the strongest staining in G2 phase and weakest/negative staining in G1. The centromeres are positive only in prometaphase and metaphase, revealing multiple aligned small and faint dots.

Cytofilament (AC-15/AC-16/AC-17)

Cytoskeleton staining with variable intensity interphase cells

Cytoskeleton staining with variable intensity in interphase cells

Cytoplasmic discrete dots/GW body-like (AC-18)

Discrete dots in cytoplasm of interphase cells

Staining of GW bodies in the cytoplasm of interphase cells with high numbers in late S/G2 cells

Cytoplasmic dense fine speckled (or homogeneous,AC-19)

Uniform diffuse staining of the cytoplasm in interphase

Uniform diffuse staining of the cytoplasm in interphase cells

Speckled (AC-20)

Speckles Speckled staining of the cytoplasm

Scattered small speckles in the cytoplasm

Mitochondria-like (AC-21)

Coarse granular filamentous staining

Coarse granular filamentous staining

Golgi complex (AC-22)

Discontinuous speckled or granular perinuclear staining

Discontinuous speckled or granular perinuclear staining

Rods/Rings (AC-23)

Distinct rod and ring structures throughout the cytoplasm

Distinct rod and ring structures throughout the cytoplasm

 

Centrosome (AC-24)

Distinct dots (2-4/cell) in cytoplasm and at the poles of mitotic spindle

Distinct dots (2-4/cell) in cytoplasm and at the poles of mitotic spindle

Spindle fibers (AC-25)

The spindle fibers between the poles are stained in mitotic cells, associated

The spindle fibers between the poles are stained in mitotic cells, associated with cone-shaped decoration of the mitotic poles. Spindle fibers cover both NuMA-like and non-NuMA patterns. NuMA-like pattern has associated distinct nuclear speckles. Only non-NuMA patterns are shown here while NuMA-like patterns are shown in the NuMA-like group

NuMA-like (AC-26)

https://www.anapatterns.org/imgNew/prontas/1473306362-0.jpg?1532829908

                        

Nuclear speckled staining with spindle fibers

Intercellular bridge (AC-27)

 Staining of the intercellular bridge that connects daughter cells by the end of cell division, but before cell separation

Staining of the intercellular bridge that connects daughter cells by the end of cell division, but before cell separation

Mitotic Chromosomal (AC-28)

Diffuse staining of condensed chromatin in mitotic cells

 

 

References

Codebook and Frequencies

SEQN - Respondent sequence number

Variable Name:
SEQN
SAS Label:
Respondent sequence number
English Text:
Respondent sequence number.
Target:
Both males and females 12 YEARS - 150 YEARS

WTANA6YR - Six-year SSANA subsample weights

Variable Name:
WTANA6YR
SAS Label:
Six-year SSANA subsample weights
English Text:
Six-year SSANA subsample weights
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
1559.465103 to 262789.6562 Range of Values 4754 4754
0 No Lab Result 0 4754
. Missing 0 4754

SSCYT - total cytoplasm intensity

Variable Name:
SSCYT
SAS Label:
total cytoplasm intensity
English Text:
total cytoplasm intensity
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSNUC - total nucleus intensity

Variable Name:
SSNUC
SAS Label:
total nucleus intensity
English Text:
total nucleus intensity
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSTOMIC - total mitotic intensity

Variable Name:
SSTOMIC
SAS Label:
total mitotic intensity
English Text:
total mitotic intensity
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSMSI - maxim signal intensity

Variable Name:
SSMSI
SAS Label:
maxim signal intensity
English Text:
maxim signal intensity
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSTSUM - titer summary

Variable Name:
SSTSUM
SAS Label:
titer summary
English Text:
titer summary
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
titer summary Value was recorded 106 106
< blank > Missing 4648 4754

SSNUCPOS - nucleus nucleolar positive

Variable Name:
SSNUCPOS
SAS Label:
nucleus nucleolar positive
English Text:
nucleus nucleolar positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSNUCSIG - nucleus nucleolar signal

Variable Name:
SSNUCSIG
SAS Label:
nucleus nucleolar signal
English Text:
nucleus nucleolar signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 3 Range of Values 4749 4749
. Missing 5 4754

SSNUHOMP - nucleus homogenous positive

Variable Name:
SSNUHOMP
SAS Label:
nucleus homogenous positive
English Text:
nucleus homogenous positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSNUHOMS - nucleus homogenous signal

Variable Name:
SSNUHOMS
SAS Label:
nucleus homogenous signal
English Text:
nucleus homogenous signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSNDFSPS - nucleus dense fine speckles positive

Variable Name:
SSNDFSPS
SAS Label:
nucleus dense fine speckles positive
English Text:
nucleus dense fine speckles positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSNDSPSG - nucleus dense fine speckles signal

Variable Name:
SSNDSPSG
SAS Label:
nucleus dense fine speckles signal
English Text:
nucleus dense fine speckles signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSNFSPOS - nucleus fine speckles positive

Variable Name:
SSNFSPOS
SAS Label:
nucleus fine speckles positive
English Text:
nucleus fine speckles positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSNFSPSG - nucleus fine speckles signal

Variable Name:
SSNFSPSG
SAS Label:
nucleus fine speckles signal
English Text:
nucleus fine speckles signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSNUCSPP - nucleus coarse speckles positive

Variable Name:
SSNUCSPP
SAS Label:
nucleus coarse speckles positive
English Text:
nucleus coarse speckles positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSNUCSPS - nucleus coarse speckles signal

Variable Name:
SSNUCSPS
SAS Label:
nucleus coarse speckles signal
English Text:
nucleus coarse speckles signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSNUCENP - nucleus centromere positive

Variable Name:
SSNUCENP
SAS Label:
nucleus centromere positive
English Text:
nucleus centromere positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSNUCENS - nuclear centomere signal

Variable Name:
SSNUCENS
SAS Label:
nuclear centomere signal
English Text:
nuclear centomere signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSNUDOTP - nuclear dots positive

Variable Name:
SSNUDOTP
SAS Label:
nuclear dots positive
English Text:
nuclear dots positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSNUDOTS - nuclear dots signal

Variable Name:
SSNUDOTS
SAS Label:
nuclear dots signal
English Text:
nuclear dots signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 3 Range of Values 4749 4749
. Missing 5 4754

SSNUENVP - nuclear envelope positive

Variable Name:
SSNUENVP
SAS Label:
nuclear envelope positive
English Text:
nuclear envelope positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSNUENVS - nuclear envelope signal

Variable Name:
SSNUENVS
SAS Label:
nuclear envelope signal
English Text:
nuclear envelope signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSNPSPOS - nucleus PCNA-Like positive

Variable Name:
SSNPSPOS
SAS Label:
nucleus PCNA-Like positive
English Text:
nucleus PCNA-Like positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSNPSSIG - nucleus PCNP-Like signal

Variable Name:
SSNPSSIG
SAS Label:
nucleus PCNP-Like signal
English Text:
nucleus PCNP-Like signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 2 Range of Values 4749 4749
. Missing 5 4754

SSCENPOS - nucleus CEN-F-like positive

Variable Name:
SSCENPOS
SAS Label:
nucleus CEN-F-like positive
English Text:
nucleus CEN-F-like positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 0 4749 4749
. Missing 5 4754

SSCENSIG - nucleus CEC-F like signal

Variable Name:
SSCENSIG
SAS Label:
nucleus CEC-F like signal
English Text:
nucleus CEC-F like signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 0 4749 4749
. Missing 5 4754

SSCYHOMP - cytoplasm homogeneous positive

Variable Name:
SSCYHOMP
SAS Label:
cytoplasm homogeneous positive
English Text:
cytoplasm homogeneous positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSCYHOMS - cytoplasm homogeneous signal

Variable Name:
SSCYHOMS
SAS Label:
cytoplasm homogeneous signal
English Text:
cytoplasm homogeneous signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSCYSPS - cytoplasm speckled positive

Variable Name:
SSCYSPS
SAS Label:
cytoplasm speckled positive
English Text:
cytoplasm speckled positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSCYTSG - cytoplasm speckled signal

Variable Name:
SSCYTSG
SAS Label:
cytoplasm speckled signal
English Text:
cytoplasm speckled signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 3 Range of Values 4749 4749
. Missing 5 4754

SSCYMIP - cytoplasm mitochondria-like positive

Variable Name:
SSCYMIP
SAS Label:
cytoplasm mitochondria-like positive
English Text:
cytoplasm mitochondria-like positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSCYMIS - cytoplasm mitochondria-like signal

Variable Name:
SSCYMIS
SAS Label:
cytoplasm mitochondria-like signal
English Text:
cytoplasm mitochondria-like signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 3 Range of Values 4749 4749
. Missing 5 4754

SSCYGOP - cytoplasm golgi complex positive

Variable Name:
SSCYGOP
SAS Label:
cytoplasm golgi complex positive
English Text:
cytoplasm golgi complex positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSCYGOS - cytoplasm golgi complex signal

Variable Name:
SSCYGOS
SAS Label:
cytoplasm golgi complex signal
English Text:
cytoplasm golgi complex signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 2 Range of Values 4749 4749
. Missing 5 4754

SSCYGWP - cytoplasm GW body positive

Variable Name:
SSCYGWP
SAS Label:
cytoplasm GW body positive
English Text:
cytoplasm GW body positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSCYGWS - cytoplasm GW body signal

Variable Name:
SSCYGWS
SAS Label:
cytoplasm GW body signal
English Text:
cytoplasm GW body signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 3 Range of Values 4749 4749
. Missing 5 4754

SSCYFLPS - cytoplasm cytofilament positive

Variable Name:
SSCYFLPS
SAS Label:
cytoplasm cytofilament positive
English Text:
cytoplasm cytofilament positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSCYFLSG - cytoplasm cytofilament signal

Variable Name:
SSCYFLSG
SAS Label:
cytoplasm cytofilament signal
English Text:
cytoplasm cytofilament signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 3 Range of Values 4749 4749
. Missing 5 4754

SSCYRRPS - cytoplasm rods/rings positive

Variable Name:
SSCYRRPS
SAS Label:
cytoplasm rods/rings positive
English Text:
cytoplasm rods/rings positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSCYRRSG - cytoplasm rods/rings signal

Variable Name:
SSCYRRSG
SAS Label:
cytoplasm rods/rings signal
English Text:
cytoplasm rods/rings signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSMTCNPS - mitotic centrosome positive

Variable Name:
SSMTCNPS
SAS Label:
mitotic centrosome positive
English Text:
mitotic centrosome positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSMTCNSG - mitotic centrosome signal

Variable Name:
SSMTCNSG
SAS Label:
mitotic centrosome signal
English Text:
mitotic centrosome signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 3 Range of Values 4749 4749
. Missing 5 4754

SSMISFPS - mitotic spindle fibers positive

Variable Name:
SSMISFPS
SAS Label:
mitotic spindle fibers positive
English Text:
mitotic spindle fibers positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSMISFSG - mitotic spindle fibers signal

Variable Name:
SSMISFSG
SAS Label:
mitotic spindle fibers signal
English Text:
mitotic spindle fibers signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSMTNMPS - mitotic NuMa positive

Variable Name:
SSMTNMPS
SAS Label:
mitotic NuMa positive
English Text:
mitotic NuMa positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSMTNMSG - mitotic NuMa signal

Variable Name:
SSMTNMSG
SAS Label:
mitotic NuMa signal
English Text:
mitotic NuMa signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754

SSMTBRPS - mitotic intracellular bridge positive

Variable Name:
SSMTBRPS
SAS Label:
mitotic intracellular bridge positive
English Text:
mitotic intracellular bridge positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 0 4749 4749
. Missing 5 4754

SSMTBRSG - mitotic intracellular bridge signal

Variable Name:
SSMTBRSG
SAS Label:
mitotic intracellular bridge signal
English Text:
mitotic intracellular bridge signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 0 4749 4749
. Missing 5 4754

SSMICHP - mitotic chromosomes positive

Variable Name:
SSMICHP
SAS Label:
mitotic chromosomes positive
English Text:
mitotic chromosomes positive
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 1 Range of Values 4749 4749
. Missing 5 4754

SSMICHS - mitotic chromosomes signal

Variable Name:
SSMICHS
SAS Label:
mitotic chromosomes signal
English Text:
mitotic chromosomes signal
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 to 4 Range of Values 4749 4749
. Missing 5 4754