Table of Contents

Component Description

Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (PCBs) [coplanar] are similar classes of chlorinated aromatic chemicals that are produced as contaminants or byproducts. They have no known commercial or natural use. Dioxins are produced primarily during the incineration or burning of waste; the bleaching processes used in pulp and paper mills; and the chemical syntheses of trichlorophenoxyacetic acid, hexachlorophene, vinyl chloride, trichlorophenol, and pentachlorophenol. Both the synthesis and heat-related degradation of PCBs will produce PCDF by-products. PCBs are chlorinated aromatic hydrocarbon chemicals that were once synthesized for use as heat-exchanger, transformer, and hydraulic fluids, and also used as additives to paints, oils, window caulking, and floor tiles.

Production of PCBs peaked in the early 1970s and was banned in the United States after 1979. Together with the PCDDs and PCDFs, cPCBs and mPCBs are often referred to as “dioxin-like” chemicals because they act in the body through a similar mechanism.

In the environment, these dioxin-like chemicals are persistent and usually occur as a mixture of congeners (i.e., compounds that differ by the numbers and positions of chlorine atoms attached to the dibenzo-p-dioxin, dibenzofuran, or biphenyl structures). The general population is exposed to low levels of these dioxin-like chemicals primarily through ingestion of high-fat foods such as dairy products, eggs, and animal fats, and some fish and wildlife.

Eligible Sample

Examined participants aged 12 years and older from a one-third sample were eligible.

Description of Laboratory Methodology

The seventeen PCDDs/PCDFs, and three cPCBs were measured in serum by gas chromatography/isotope-dilution high-resolution mass spectrometry (GC/ID-HRMS). The analytical method for PCDDs/PCDFs/cPCB is described in Patterson et al., 1992 and Turner et al., 1994. Reported results met the Division of Laboratory Sciences’ quality control and quality assurance performance criteria for accuracy and precision (similar to specifications outlined by Westgard, 1981).

Refer to the Laboratory Method Files for a detailed description of the laboratory methods used.

There were no changes to the lab method, lab equipment, or lab site for this component in the NHANES 2009-2010 cycle.

Laboratory Method Files

PBDDs,PCDFs and cPCBs (September 2017)

Laboratory Quality Assurance and Monitoring

Serum samples were processed, stored, and shipped to the Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA for analysis.

Detailed instructions on specimen collection and processing are discussed in the NHANES Laboratory Procedure Manual (LPM). Vials are stored under appropriate frozen (-30ºC) conditions until they are shipped to the National Center for Environmental Health for testing.

The NHANES quality assurance and quality control (QA/QC) protocols meet the 1988 Clinical Laboratory Improvement Act mandates. Detailed QA/QC instructions are discussed in the NHANES LPM.

Mobile Examination Centers (MECs)

Laboratory team performance is monitored using several techniques. NCHS and contract consultants use a structured competency assessment evaluation during visits to evaluate both the quality of the laboratory work and the quality-control procedures. Each laboratory staff member is observed for equipment operation, specimen collection and preparation; testing procedures and constructive feedback are given to each staff member. Formal retraining sessions are conducted annually to ensure that required skill levels were maintained.

Analytical Laboratories

NHANES uses several methods to monitor the quality of the analyses performed by the contract laboratories. In the MEC, these methods include performing blind split samples collected during “dry run” sessions. In addition, contract laboratories randomly perform repeat testing on 2% of all specimens.

NCHS developed and distributed a quality control protocol for all CDC and contract laboratories, which outlined the use of Westgard rules (Westgard, et al. 1981) when running NHANES specimens. Progress reports containing any problems encountered during shipping or receipt of specimens, summary statistics for each control pool, QC graphs, instrument calibration, reagents, and any special considerations are submitted to NCHS quarterly. The reports are reviewed for trends or shifts in the data. The laboratories are required to explain any identified areas of concern.

All QC procedures recommended by the manufacturers were followed. Reported results for all assays meet the Division of Environmental Health Laboratory Sciences’ quality control and quality assurance performance criteria for accuracy and precision, similar to the Westgard rules (Caudill, et al. 2008).

Data Processing and Editing

The data were reviewed. Incomplete data or improbable values were sent to the performing laboratory for confirmation.

Analytic Notes

Refer to the 2009-2010 Laboratory Data Overview for general information on NHANES laboratory data.

Other data set: Additional PCB congeners are reported under data file name PCBPOL_F. Among these PCB congeners PCB 105, 114, 118, 156, 157, 167 and 189 has a toxic equivalence factor (TEF) and may be used with this data set for calculating a total TCDD equivalence.

Subsample Weights

PCDDs, PCDFs, and cPCBs were measured in a one-third subsample of participants 12 years and older. Special sample weights are required to analyze these data properly. Specific sample weights for this subsample are included in this data file and should be used when analyzing these data.

Samples were pooled in groups of 8 samples per pool within 40 demographic groups. The analysis of NHANES 2009-2010 pooled-sample data must be conducted with the basic demographic variables provided in this data file. This pooled-sample data file cannot be linked to other NHANES 2009-2010 data. Because each sample person does not have an equal probability of selection, sample weighting is needed to produce correct population estimates of means, percentiles, and other descriptive statistics.

The pooled-sample weights required to produce estimates from these data are included in this data file. The analysis of pooled-samples from survey data is a relatively new field of study, and there is currently no established method to produce design effect adjusted variance estimates for these pooled results. These data cannot be analyzed using software designed for complex surveys because design features are not available.

Rationale and Methods Used to Create Pooled Results

The Centers for Disease Control and Prevention (CDC) provides an ongoing assessment of the US population's exposure to environmental chemicals by using biomonitoring in conjunction with CDC's National Health and Nutrition Examination Survey (NHANES). Characterizing the distributions of concentrations of environmental compounds or their metabolites in the US population is a primary objective of CDC's biomonitoring program. Historically, this characterization has been based on individual measurements of these compounds in body fluid or tissue from representative samples of the population. Pooling samples allows for larger sample volumes which can result in lower limits of detection and reduces the number of measurements and costs. In NHANES 2009-2010, a weighted pooled-sample design was implemented to facilitate pooling samples before making analytical measurements. Table 1 lists the International Union of Pure and Applied Chemistry (IUPAC) names, common abbreviation, and NHANES variable name for the analytes included in this data file.

Pools were prepared from serum collected from a random one-third subset of the NHANES 2009-2010 participants aged 12 years and older. Samples were pooled based on gender, race and Hispanic origin, and age. To implement the pooled-sample design, each participant sample was identified as belonging to one of 40 demographic groups based on race and Hispanic origin (Mexican American: MA, Other Hispanic: OH, non-Hispanic white: NHW, non-Hispanic black: NHB, Other race including multiracial: OTHER), gender (Male, Female), and age group (12-19, 20-39, 40-59, and 60+ years of age and older). Eight (8) samples were included in each pool. The number of pools created for each of the 40 demographic groups varied depending on the total number of individual samples available in a demographic group. The one-third subset of NHANES 2009-2010 represents 2524 individual samples, but because the pooled-sample design requires that all samples be of sufficient volume and that there be the same number of samples in each pool, 2322 samples were available to create 301 pools with 8 samples per pool (Exceptions are in Table 2). The variable SAMPLEID denotes the identification number for each pool and ranges from 1 through 303, excluding the numbers 265 and 266. Please refer to the Pooled-Sample Technical Support file (POOLTF_F) for detailed information on individual participants included in each pool.

In order to incorporate sample weighting into the pooled-sample design it was necessary to use a different volume of material from each sample contributing to a pool. The volume chosen for each sample in a pool was based on the ratio of its sampling weight to the sum of the sampling weights of all samples in the pool. To physically accomplish the pooling in the laboratory required that the ratio of the largest to the smallest sampling weight of samples in the same pool be no larger than about 4 or 5. The individual samples were sorted/stratified by sampling weight within each of the 40 demographic groups and pools were formed using samples with sampling weights adjacent to one another in the sorted list. The number of samples in the one-third subset, number of samples available, the number of these samples that were usable, and the number of pools formed in each demographic group are presented in Table 2. Once the pools were created, summed sampling weights were further adjusted to account for the unused samples. These adjusted summed sampling weights are represented by the variable named WTSMSMPA.

Detection Limits

In the dataset, the whole-weight detection limit (pg/g serum) is a variable and dependent on the available sample size; however, the variation in sample size was low. Lipid adjusted detection limits are variable (ng/g lipid) due to differences of the lipid levels measured in individual pools/specimens. In cases where the result was below the limit of detection, the value for that variable is the detection limit divided by the square root of 2.

Table 1. NHANES Variable name, common abbreviation and International Union of Pure and Applied Chemistry (IUPAC) name for each analyte reported. Maximum limit of detection (MLOD) expressed as pg/serum and ng/g lipid).

Variable Name Common Abbrev. IUPAC Name Max LOD (fg/g serum) Max LOD (pg/g lipid)
LBCD01 12378-PeCDD 1,2,3,7,8-Pentachlorodibenzo-p-dioxin 5.4 1.10
LBCD02 123478-HxCDD 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin 1.3 0.28
LBCD03 123678-HxCDD 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin 1 0.22
LBCD04 123789-HxCDD 1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin 0.7 0.14
LBCD05 1234678-HpCDD 1,2,3,4,6,7,8-Heptachlorodibenzo-p-dioxin 21 4.50
LBCD07 OCDD Octachlorodibenzo-p-dioxin 110 24.00
LBCF01 2378-TeCDF 2,3,7,8-Tetrachlorodibenzofuran 2.2 0.48
LBCF02 12378-PeCDF 1,2,3,7,8-Pentachlorodibenzofuran 4 0.85
LBCF03 23478-PeCDF 2,3,4,7,8-Pentachlorodibenzofuran 4.4 0.92
LBCF04 123478-HxCDF 1,2,3,4,7,8-Hexachlorodibenzofuran 2.5 0.55
LBCF05 123678-HxCDF 1,2,3,6,7,8-Hexachlorodibenzofuran 0.8 0.19
LBCF06 123789-HxCDF 1,2,3,7,8,9-Hexachlorodibenzofuran 1.8 0.37
LBCF07 234678-HxCDF 2,3,4,6,7,8-Hexchlorodibenzofuran 1 0.21
LBCF08 1234678-HpCDF 1,2,3,4,6,7,8-Heptachlorodibenzofuran 9.2 1.90
LBCF09 1234789-HpCDF 1,2,3,4,7,8,9-Heptachlorodibenzofuran 1.6 0.35
LBCF10 OCDF Octachlorodibenzofuran 12 2.60
LBCTC2 PCB81 3,4,4´,5-Tetrachlorobiphenyl 16 3.50
LBCPCB PCB126 3,3´,4,4´,5-Pentachlorobiphenyl 11 2.50
LBCHXC PCB169 3,3´,4,4´,5,5´-Hexachlorobiphenyl 11 2.50
LBCTCD 2378-TeCDD 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) 3.7 0.78

 

Table 2. Number of subjects in the one-third subsample, number of individual serum samples available, number of usable samples, and number of pools formed from NHANES 2009-2010 participants per demographic group.

 

 

 

Race/ Ethnicity

 

 

 

Gender

 

Number of subjects in the one-third subsample/

Number of Samples Available/Number of Usable Samples

(Number of Pools)

12–19 years

(RIDAGEYR=1)1

20–39 years

(RIDAGEYR=2)

40–59 years

(RIDAGEYR=3)

60+ years

(RIDAGEYR=4)

Mexican

American

(RIDRETH1=1)1

Male

(RIAGENDR=1)1

65/61/602

(8)

67/65/64

(8)

70/65/64

(8)

43/40/40

(5)

Female

(RIAGENDR=2)

57/52/523

(7)

80/76/764

(10)

73/72/72

(9)

51/49/48

(6)

Other Hispanics

(RIDRETH1=2)

Male

(RIAGENDR=1)

22/20/205

(3)

35/34/346

(5)

40/39/397

(5)

26/24/24

(3)

Female

(RIAGENDR=2)

22/20/205

(3)

38/33/32

(4)

39/34/348

(5)

38/35/359

(5)

Non-Hispanic White

(RIDRETH1=3)

Male

(RIAGENDR=1)

91/79/7910

(10)

139/135/13511

(17)

146/142/136

(17)

182/175/168

(21)

Female

(RIAGENDR=2)

76/65/6312

(8)

164/151/15013

(19)

149/138/136

(17)

188/178/176

(22)

 

Non-Hispanic Black

(RIDRETH1=4)

Male

(RIAGENDR=1)

45/43/4314

(6)

56/52/523

(7)

60/54/5415

(7)

72/67/6716

(9)

Female

(RIAGENDR=2)

53/48/48

(6)

63/57/56

(7)

60/53/5317

(7)

58/52/523

(7)

Other Race including Multiracial

(RIDRETH1=5)

Male

(RIAGENDR=1)

13/11/1118

(2)

21/19/1819

(3)

18/18/16

(2)

16/15/1520

(2)

Female

(RIAGENDR=2)

18/17/16

(2)

31/30/3021

(4)

23/21/2122

(3)

16/15/1323

(2)

 

  1 Value of this categorical variable in the data set.

  2 With only 60 usable samples, seven 8 sample pools and one 4 sample pool were created.

  3 With only 52 usable samples, six 8 sample pools and one 4 sample pool were created.

  4 With only 76 usable samples, nine 8 sample pools and one 4 sample pool were created.

  5 With only 20 usable samples, two 8 sample pools and one 4 sample pool were created.

  6 With only 34 usable samples, three 8 sample pools and two 5 sample pools were created.

  7 With only 39 usable samples, four 8 sample pools and one 7 sample pool were created.

  8 With only 34 usable samples, four 8 sample pools and one 2 sample pool were created.

  9 With only 35 usable samples, four 8 sample pools and one 3 sample pool were created.

10 With only 79 usable samples, nine 8 sample pools and one 7 sample pool were created.

11 With only 135 usable samples sixteen 8 sample pools and one 7 sample pool were created.

12 With only 63 usable samples, seven 8 sample pools and one 7 sample pool were created.

13 With only 150 usable samples, eighteen 8 sample pools and one 6 sample pool were created.

14 With only 34 usable samples, five 8 sample pools and one 3 sample pool were created.

15 With only 54 usable samples, six 8 sample pools and one 6 sample pool were created.

16 With only 67 usable samples, eight 8 sample pools and one 3 sample pool were created.

17 With only 53 usable samples, six 8 sample pools and one 5 sample pool were created.

18 With only 11 usable samples, one 6 sample pool and one 5 sample pool were created.

19 With only 18 usable samples, one 8 sample pool, one 6 sample pool, and one 4 sample pool were created.

20 With only 15 usable samples, one 8 sample pool and one 7 sample pool were created.

21 With only 30 usable samples, three 8 sample pools and one 6 sample pool were created.

22 With only 21 usable samples, two 8 sample pools and one 5 sample pool were created. 

23 With only 13 usable samples, one 8 sample pools and one 5 sample pool were created.


Methodological approaches for analysis

There are a few pooled-sample methodological publications which address approaches related to the following topics:

    • Variance estimation and bias correction when pooling samples from log-normally distributed populations (Caudill, 2010a; Caudill, 2010b; Caudill et al., 2007; Li et al., 2014);

    • Models that incorporate measurement error when analyzing pooled-samples from normally or log-normally distributed populations (Caudill, 2010a);

    • Incorporation of sample weighting into a pooled-sample design (Caudill, 2012; Caudill, 2010a);

    • Estimation of standard errors and confidence limits for point estimates from pooled-samples (Caudill, 2012; Caudill, 2010a).

References

Codebook and Frequencies

SAMPLEID - Pool identification number

Variable Name:
SAMPLEID
SAS Label:
Pool identification number
English Text:
Pool identification number
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
1 to 303 Range of Values 301 301
. Missing 0 301

RIAGENDR - Gender

Variable Name:
RIAGENDR
SAS Label:
Gender
English Text:
Gender
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
1 Male 148 148
2 Female 153 301
. Missing 0 301

RIDRETH1 - Ethnicity - Recode

Variable Name:
RIDRETH1
SAS Label:
Ethnicity - Recode
English Text:
Ethnicity - Recode
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
1 Mexican American 61 61
2 Other Hispanic 33 94
3 Non-Hispanic White 131 225
4 Non-Hispanic Black 56 281
5 Other Race, Including Multiracial 20 301
. Missing 0 301

RIDAGGRP - Age at Screening Adjudicated - Recode

Variable Name:
RIDAGGRP
SAS Label:
Age at Screening Adjudicated - Recode
English Text:
Age at Screening Adjudicated - Recode
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
1 12-19 55 55
2 20-39 84 139
3 40-59 80 219
4 60+ 82 301
. Missing 0 301

RIANSMP - Number of samples in a pool

Variable Name:
RIANSMP
SAS Label:
Number of samples in a pool
English Text:
Number of samples in a pool
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
2 to 8 Range of Values 301 301
. Missing 0 301

WTSMSMPA - Sum of adjusted subsample weights

Variable Name:
WTSMSMPA
SAS Label:
Sum of adjusted subsample weights
English Text:
Adjust sum sampling weights in same pool
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
49070.542891 to 2980185.9468 Range of Values 301 301
. Missing 0 301

LBCD01 - 1,2,3,7,8-pncdd (fg/g)

Variable Name:
LBCD01
SAS Label:
1,2,3,7,8-pncdd (fg/g)
English Text:
1,2,3,7,8-Pentachlorodibenzo-p-dioxin (pncdd) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
1.556 to 67.65 Range of Values 292 292
. Missing 9 301

LBCD02 - 1,2,3,4,7,8-hxcdd (fg/g)

Variable Name:
LBCD02
SAS Label:
1,2,3,4,7,8-hxcdd (fg/g)
English Text:
1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin (hxcdd)(fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.3677 to 55.98 Range of Values 297 297
. Missing 4 301

LBCD03 - 1,2,3,6,7,8-hxcdd (fg/g)

Variable Name:
LBCD03
SAS Label:
1,2,3,6,7,8-hxcdd (fg/g)
English Text:
1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (hxcdd)(fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.2899 to 388 Range of Values 298 298
. Missing 3 301

LBCD04 - 1,2,3,7,8,9-hxcdd (fg/g)

Variable Name:
LBCD04
SAS Label:
1,2,3,7,8,9-hxcdd (fg/g)
English Text:
1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin (hxcdd) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.1909 to 57.72 Range of Values 297 297
. Missing 4 301

LBCD05 - 1,2,3,4,6,7,8-hpcdd (fg/g)

Variable Name:
LBCD05
SAS Label:
1,2,3,4,6,7,8-hpcdd (fg/g)
English Text:
1,2,3,4,6,7,8-Heptachlororodibenzo-p-dioxin (hpcdd) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
6.01 to 490.2 Range of Values 291 291
. Missing 10 301

LBCD07 - 1,2,3,4,6,7,8,9-ocdd (fg/g)

Variable Name:
LBCD07
SAS Label:
1,2,3,4,6,7,8,9-ocdd (fg/g)
English Text:
1,2,3,4,6,7,8,9-Octachlorodibenzo-p-dioxin (ocdd) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
31.82 to 7531 Range of Values 297 297
. Missing 4 301

LBCF01 - 2,3,7,8-Tetrachlorofuran (tcdf) (fg/g)

Variable Name:
LBCF01
SAS Label:
2,3,7,8-Tetrachlorofuran (tcdf) (fg/g)
English Text:
2,3,7,8-Tetrachlorodibenzofuran (tcdf) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.6152 to 8.269 Range of Values 285 285
. Missing 16 301

LBCF02 - 1,2,3,7,8-Pentachlorofuran(pncdf) (fg/g)

Variable Name:
LBCF02
SAS Label:
1,2,3,7,8-Pentachlorofuran(pncdf) (fg/g)
English Text:
1,2,3,7,8-Pentachlorodibenzofuran (pncdf) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
1.131 to 8.594 Range of Values 288 288
. Missing 13 301

LBCF03 - 2,3,4,7,8-Pentachlorofuran(pncdf) (fg/g)

Variable Name:
LBCF03
SAS Label:
2,3,4,7,8-Pentachlorofuran(pncdf) (fg/g)
English Text:
2,3,4,7,8-Pentachlorodibenzofuran (pncdf) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
1.273 to 85.65 Range of Values 298 298
. Missing 3 301

LBCF04 - 1,2,3,4,7,8-hcxdf (fg/g)

Variable Name:
LBCF04
SAS Label:
1,2,3,4,7,8-hcxdf (fg/g)
English Text:
1,2,3,4,7,8-Hexachlorodibenzofuran (hcxdf) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.7071 to 47.8 Range of Values 290 290
. Missing 11 301

LBCF05 - 1,2,3,6,7,8-hxcdf (fg/g)

Variable Name:
LBCF05
SAS Label:
1,2,3,6,7,8-hxcdf (fg/g)
English Text:
1,2,3,6,7,8-Hexachlorodibenzofuran (hxcdf) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.2475 to 47.84 Range of Values 299 299
. Missing 2 301

LBCF06 - 1,2,3,7,8,9-Hexachlorodifuran(fg/g)

Variable Name:
LBCF06
SAS Label:
1,2,3,7,8,9-Hexachlorodifuran(fg/g)
English Text:
1,2,3,7,8,9-Hexachlorodibenzofuran (hxcdf) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.4879 to 2.492 Range of Values 288 288
. Missing 13 301

LBCF07 - 2,3,4,6,7,8-Hexchlorofuran(hxcdf)(fg/g)

Variable Name:
LBCF07
SAS Label:
2,3,4,6,7,8-Hexchlorofuran(hxcdf)(fg/g)
English Text:
2,3,4,6,7,8-Hexchlorodibenzofuran (hxcdf) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.2687 to 15.38 Range of Values 297 297
. Missing 4 301

LBCF08 - 1,2,3,4,6,7,8-Heptachlorodifuran (fg/g)

Variable Name:
LBCF08
SAS Label:
1,2,3,4,6,7,8-Heptachlorodifuran (fg/g)
English Text:
1,2,3,4,6,7,8-Heptachlorodibenzofuran (hpcdf) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
2.546 to 99.01 Range of Values 299 299
. Missing 2 301

LBCF09 - 1,2,3,4,7,8,9-Heptachlorodifuran (fg/g)

Variable Name:
LBCF09
SAS Label:
1,2,3,4,7,8,9-Heptachlorodifuran (fg/g)
English Text:
1,2,3,4,7,8,9-Heptachlorodibenzofuran (hpcdf) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.4596 to 3.942 Range of Values 290 290
. Missing 11 301

LBCF10 - 1,2,3,4,6,7,8,9-Octachlorodifuran (fg/g)

Variable Name:
LBCF10
SAS Label:
1,2,3,4,6,7,8,9-Octachlorodifuran (fg/g)
English Text:
1,2,3,4,6,7,8,9-Octachlorodibenzofuran (ocdf) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
3.253 to 12.02 Range of Values 288 288
. Missing 13 301

LBCHXC - 3,3',4,4',5,5'-hexachlorobiphenyl (fg/g)

Variable Name:
LBCHXC
SAS Label:
3,3',4,4',5,5'-hexachlorobiphenyl (fg/g)
English Text:
3,3',4,4',5,5'-hexachlorobiphenyl (hxcb) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
3.253 to 340 Range of Values 293 293
. Missing 8 301

LBCPCB - 3,3',4,4',5-Pentachlorobiphenyl (fg/g)

Variable Name:
LBCPCB
SAS Label:
3,3',4,4',5-Pentachlorobiphenyl (fg/g)
English Text:
3,3',4,4',5-Pentachlorobiphenyl (pncb) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
3.253 to 680 Range of Values 294 294
. Missing 7 301

LBCTC2 - 3,4,4',5-Tetrachlorobiphenyl(tcb) (fg/g)

Variable Name:
LBCTC2
SAS Label:
3,4,4',5-Tetrachlorobiphenyl(tcb) (fg/g)
English Text:
3,4,4',5-Tetrachlorobiphenyl (tcb) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
4.455 to 35.87 Range of Values 295 295
. Missing 6 301

LBCTCD - 2,3,7,8-Tetrachloro-p-dioxn(tcdd) (fg/g)

Variable Name:
LBCTCD
SAS Label:
2,3,7,8-Tetrachloro-p-dioxn(tcdd) (fg/g)
English Text:
2,3,7,8-Tetrachlorodienzo-p-dioxin (tcdd) (fg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.9899 to 28.38 Range of Values 290 290
. Missing 11 301

LBCD01LA - 1,2,3,7,8-pncdd lipid adjusted (pg/g)

Variable Name:
LBCD01LA
SAS Label:
1,2,3,7,8-pncdd lipid adjusted (pg/g)
English Text:
1,2,3,7,8-Pentachlorodibenzo-p-dioxin (pncdd) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.2475 to 12.74 Range of Values 292 292
. Missing 9 301

LBCD02LA - 1,2,3,4,7,8-hxcdd lipid adjusted (pg/g)

Variable Name:
LBCD02LA
SAS Label:
1,2,3,4,7,8-hxcdd lipid adjusted (pg/g)
English Text:
1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin (hxcdd) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.0601 to 10.54 Range of Values 297 297
. Missing 4 301

LBCD03LA - 1,2,3,6,7,8-hxcdd lipid adjusted (pg/g)

Variable Name:
LBCD03LA
SAS Label:
1,2,3,6,7,8-hxcdd lipid adjusted (pg/g)
English Text:
1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (hxcdd) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.04738 to 73.05 Range of Values 298 298
. Missing 3 301

LBCD04LA - 1,2,3,7,8,9-hxcdd lipid adjusted (pg/g)

Variable Name:
LBCD04LA
SAS Label:
1,2,3,7,8,9-hxcdd lipid adjusted (pg/g)
English Text:
1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin (hxcdd) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.03111 to 10.68 Range of Values 297 297
. Missing 4 301

LBCD05LA - 1,2,3,4,6,7,8-hpcdd lipid adjust (pg/g)

Variable Name:
LBCD05LA
SAS Label:
1,2,3,4,6,7,8-hpcdd lipid adjust (pg/g)
English Text:
1,2,3,4,6,7,8-Heptachlororodibenzo-p-dioxin (hpcdd) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.9899 to 90.72 Range of Values 291 291
. Missing 10 301

LBCD07LA - 1,2,3,4,6,7,8,9-ocdd lipid adjust (pg/g)

Variable Name:
LBCD07LA
SAS Label:
1,2,3,4,6,7,8,9-ocdd lipid adjust (pg/g)
English Text:
1,2,3,4,6,7,8,9-Octachlorodibenzo-p-dioxin (ocdd) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
5.233 to 1418 Range of Values 297 297
. Missing 4 301

LBCF01LA - 2,3,7,8-tcdf lipid adjusted (pg/g)

Variable Name:
LBCF01LA
SAS Label:
2,3,7,8-tcdf lipid adjusted (pg/g)
English Text:
2,3,7,8-Tetrachlorodibenzofuran (tcdf) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.08485 to 1.152 Range of Values 285 285
. Missing 16 301

LBCF02LA - 1,2,3,7,8-pncdf lipid adjusted (pg/g)

Variable Name:
LBCF02LA
SAS Label:
1,2,3,7,8-pncdf lipid adjusted (pg/g)
English Text:
1,2,3,7,8-Pentachlorodibenzofuran (pncdf) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.1414 to 1.389 Range of Values 288 288
. Missing 13 301

LBCF03LA - 2,3,4,7,8-pncdf lipid adjust (pg/g)

Variable Name:
LBCF03LA
SAS Label:
2,3,4,7,8-pncdf lipid adjust (pg/g)
English Text:
2,3,4,7,8-Pentachlorodibenzofuran (pncdf) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.2051 to 14.69 Range of Values 298 298
. Missing 3 301

LBCF04LA - 1,2,3,4,7,8-hcxdf lipid adjusted (pg/g)

Variable Name:
LBCF04LA
SAS Label:
1,2,3,4,7,8-hcxdf lipid adjusted (pg/g)
English Text:
1,2,3,4,7,8-Hexachlorodibenzofuran (hcxdf) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.1202 to 9 Range of Values 290 290
. Missing 11 301

LBCF05LA - 1,2,3,6,7,8-hxcdf lipid adjusted (pg/g)

Variable Name:
LBCF05LA
SAS Label:
1,2,3,6,7,8-hxcdf lipid adjusted (pg/g)
English Text:
1,2,3,6,7,8-Hexachlorodibenzofuran (hxcdf) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.04101 to 7.596 Range of Values 299 299
. Missing 2 301

LBCF06LA - 1,2,3,7,8,9-hxcdf lipid adjusted (pg/g)

Variable Name:
LBCF06LA
SAS Label:
1,2,3,7,8,9-hxcdf lipid adjusted (pg/g)
English Text:
1,2,3,7,8,9-Hexachlorodibenzofuran (hxcdf) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.05303 to 0.3748 Range of Values 288 288
. Missing 13 301

LBCF07LA - 2,3,4,6,7,8-hxcdf lipid adjusted (pg/g)

Variable Name:
LBCF07LA
SAS Label:
2,3,4,6,7,8-hxcdf lipid adjusted (pg/g)
English Text:
2,3,4,6,7,8-Hexchlorodibenzofuran (hxcdf) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.04101 to 2.263 Range of Values 297 297
. Missing 4 301

LBCF08LA - 1,2,3,4,6,7,8-hpcdf lipid adjust (pg/g)

Variable Name:
LBCF08LA
SAS Label:
1,2,3,4,6,7,8-hpcdf lipid adjust (pg/g)
English Text:
1,2,3,4,6,7,8-Heptachlorodibenzofuran (hpcdf) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.4172 to 19.1 Range of Values 299 299
. Missing 2 301

LBCF09LA - 1,2,3,4,7,8,9-hpcdf lipid adjust (pg/g)

Variable Name:
LBCF09LA
SAS Label:
1,2,3,4,7,8,9-hpcdf lipid adjust (pg/g)
English Text:
1,2,3,4,7,8,9-Heptachlorodibenzofuran (Hpcdf) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.0601 to 0.8898 Range of Values 290 290
. Missing 11 301

LBCF10LA - 1,2,3,4,6,7,8,9-ocdf lipid adjust (pg/g)

Variable Name:
LBCF10LA
SAS Label:
1,2,3,4,6,7,8,9-ocdf lipid adjust (pg/g)
English Text:
1,2,3,4,6,7,8,9-Octachlorodibenzofuran (ocdf) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.3606 to 2.546 Range of Values 288 288
. Missing 13 301

LBCHXCLA - 3,3',4,4',5,5'-hxcb lipid adjust (pg/g)

Variable Name:
LBCHXCLA
SAS Label:
3,3',4,4',5,5'-hxcb lipid adjust (pg/g)
English Text:
3,3',4,4',5,5'-hexachlorobiphenyl (hxcb) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.5374 to 62.34 Range of Values 293 293
. Missing 8 301

LBCPCBLA - 3,3',4,4',5-pncb lipid adjusted (pg/g)

Variable Name:
LBCPCBLA
SAS Label:
3,3',4,4',5-pncb lipid adjusted (pg/g)
English Text:
3,3',4,4',5-Pentachlorobiphenyl (pncb) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.5303 to 128.2 Range of Values 294 294
. Missing 7 301

LBCTC2LA - 3,4,4',5-tcb lipid adjusted (pg/g)

Variable Name:
LBCTC2LA
SAS Label:
3,4,4',5-tcb lipid adjusted (pg/g)
English Text:
3,4,4',5-Tetrachlorobiphenyl (tcb) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.5374 to 6.762 Range of Values 295 295
. Missing 6 301

LBCTCDLA - 2,3,7,8-tcdd lipid adjusted (pg/g)

Variable Name:
LBCTCDLA
SAS Label:
2,3,7,8-tcdd lipid adjusted (pg/g)
English Text:
2,3,7,8-Tetrachlorodienzo-p-dioxin (tcdd) Lipid Adjusted (pg/g)
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0.1697 to 5.03 Range of Values 290 290
. Missing 11 301

LBDD01LC - 1,2,3,7,8-pncdd comment code

Variable Name:
LBDD01LC
SAS Label:
1,2,3,7,8-pncdd comment code
English Text:
1,2,3,7,8-Pentachlorodibenzo-p-dioxin (pncdd) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 289 289
1 Below lower detection limit 3 292
. Missing 9 301

LBDD02LC - 1,2,3,4,7,8-hxcdd comment code

Variable Name:
LBDD02LC
SAS Label:
1,2,3,4,7,8-hxcdd comment code
English Text:
1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin (hxcdd) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 294 294
1 Below lower detection limit 3 297
. Missing 4 301

LBDD03LC - 1,2,3,6,7,8-hxcdd comment code

Variable Name:
LBDD03LC
SAS Label:
1,2,3,6,7,8-hxcdd comment code
English Text:
1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (hxcdd) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 297 297
1 Below lower detection limit 1 298
. Missing 3 301

LBDD04LC - 1,2,3,7,8,9-hxcdd comment code

Variable Name:
LBDD04LC
SAS Label:
1,2,3,7,8,9-hxcdd comment code
English Text:
1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin (hxcdd) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 296 296
1 Below lower detection limit 1 297
. Missing 4 301

LBDD05LC - 1,2,3,4,6,7,8-hpcdd comment code

Variable Name:
LBDD05LC
SAS Label:
1,2,3,4,6,7,8-hpcdd comment code
English Text:
1,2,3,4,6,7,8-Heptachlororodibenzo-p-dioxin (hpcdd) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 290 290
1 Below lower detection limit 1 291
. Missing 10 301

LBDD07LC - 1,2,3,4,6,7,8,9-ocdd comment code

Variable Name:
LBDD07LC
SAS Label:
1,2,3,4,6,7,8,9-ocdd comment code
English Text:
1,2,3,4,6,7,8,9-Octachlorodibenzo-p-dioxin (ocdd) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 296 296
1 Below lower detection limit 1 297
. Missing 4 301

LBDF01LC - 2,3,7,8-tcdf comment code

Variable Name:
LBDF01LC
SAS Label:
2,3,7,8-tcdf comment code
English Text:
2,3,7,8-Tetrachlorodibenzofuran (tcdf) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 199 199
1 Below lower detection limit 86 285
. Missing 16 301

LBDF02LC - 1,2,3,7,8-pncdf comment code

Variable Name:
LBDF02LC
SAS Label:
1,2,3,7,8-pncdf comment code
English Text:
1,2,3,7,8-Pentachlorodibenzofuran (pncdf) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 135 135
1 Below lower detection limit 153 288
. Missing 13 301

LBDF03LC - 2,3,4,7,8-pncdf comment code

Variable Name:
LBDF03LC
SAS Label:
2,3,4,7,8-pncdf comment code
English Text:
2,3,4,7,8-Pentachlorodibenzofuran (pncdf) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 294 294
1 Below lower detection limit 4 298
. Missing 3 301

LBDF04LC - 1,2,3,4,7,8-hcxdf comment code

Variable Name:
LBDF04LC
SAS Label:
1,2,3,4,7,8-hcxdf comment code
English Text:
1,2,3,4,7,8-Hexachlorodibenzofuran (hcxdf) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 289 289
1 Below lower detection limit 1 290
. Missing 11 301

LBDF05LC - 1,2,3,6,7,8-hxcdf comment code

Variable Name:
LBDF05LC
SAS Label:
1,2,3,6,7,8-hxcdf comment code
English Text:
1,2,3,6,7,8-Hexachlorodibenzofuran (hxcdf) specimen code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 298 298
1 Below lower detection limit 1 299
. Missing 2 301

LBDF06LC - 1,2,3,7,8,9-hxcdf comment code

Variable Name:
LBDF06LC
SAS Label:
1,2,3,7,8,9-hxcdf comment code
English Text:
1,2,3,7,8,9-Hexachlorodibenzofuran (hxcdf) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 13 13
1 Below lower detection limit 275 288
. Missing 13 301

LBDF07LC - 2,3,4,6,7,8-hxcdf comment code

Variable Name:
LBDF07LC
SAS Label:
2,3,4,6,7,8-hxcdf comment code
English Text:
2,3,4,6,7,8-Hexchlorodibenzofuran (hxcdf) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 290 290
1 Below lower detection limit 7 297
. Missing 4 301

LBDF08LC - 1,2,3,4,6,7,8-hpcdf comment code

Variable Name:
LBDF08LC
SAS Label:
1,2,3,4,6,7,8-hpcdf comment code
English Text:
1,2,3,4,6,7,8-Heptachlorodibenzofuran (hpcdf) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 298 298
1 Below lower detection limit 1 299
. Missing 2 301

LBDF09LC - 1,2,3,4,7,8,9-hpcdf comment code

Variable Name:
LBDF09LC
SAS Label:
1,2,3,4,7,8,9-hpcdf comment code
English Text:
1,2,3,4,7,8,9-Heptachlorodibenzofuran (hpcdf) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 184 184
1 Below lower detection limit 106 290
. Missing 11 301

LBDF10LC - 1,2,3,4,6,7,8,9-ocdf comment code

Variable Name:
LBDF10LC
SAS Label:
1,2,3,4,6,7,8,9-ocdf comment code
English Text:
1,2,3,4,6,7,8,9-Octachlorodibenzofuran (ocdf) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 11 11
1 Below lower detection limit 277 288
. Missing 13 301

LBDHXCLC - 3,3',4,4',5,5'-hxcb comment code

Variable Name:
LBDHXCLC
SAS Label:
3,3',4,4',5,5'-hxcb comment code
English Text:
3,3',4,4',5,5'-hexachlorobiphenyl (hxcb) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 292 292
1 Below lower detection limit 1 293
. Missing 8 301

LBDPCBLC - 3,3',4,4',5-pncb comment code

Variable Name:
LBDPCBLC
SAS Label:
3,3',4,4',5-pncb comment code
English Text:
3,3',4,4',5-Pentachlorobiphenyl (pncb) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 292 292
1 Below lower detection limit 2 294
. Missing 7 301

LBDTC2LC - 3,4,4',5-tcb comment code

Variable Name:
LBDTC2LC
SAS Label:
3,4,4',5-tcb comment code
English Text:
3,4,4',5-Tetrachlorobiphenyl (tcb) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 96 96
1 Below lower detection limit 199 295
. Missing 6 301

LBDTCDLC - 2,3,7,8-tcdd comment code

Variable Name:
LBDTCDLC
SAS Label:
2,3,7,8-tcdd comment code
English Text:
2,3,7,8-Tetrachlorodienzo-p-dioxin (tcdd) comment code
Target:
Both males and females 12 YEARS - 150 YEARS
Code or Value Value Description Count Cumulative Skip to Item
0 At or above the detection limit 252 252
1 Below lower detection limit 38 290
. Missing 11 301