Prostate Cancer Risk and Outcome in WTC Respondents

Project Number
Icahn School of Medicine at Mount Sinai
Fiscal Year Awarded
Project Duration
2 years


This study represents the first in-depth analysis of prostate cancer among World Trade Center (WTC) rescue and recovery workers. The study results will have practical implications on the surveillance and clinical management of prostate cancer, which is the most common cancer among male WTC Health Program members. The study will generate novel data on biomarkers of prostate cancer aggressiveness that could be used to make decisions on clinical treatment.

Research Objectives


An excess incidence of prostate cancer has been identified among World Trade Center (WTC) rescue and recovery workers included in the WTC Health Program (WTCHP) at Mount Sinai in New York. An excess has also been reported among WTC-exposed firefighters included in a separate program. It is unclear whether the excess is associated with WTC-related exposures or represents an artifact.

The objectives of this project are to elucidate the reasons for the increased incidence of prostate cancer among WTCHP participants and to explore the behavior of these cancers.


Icahn School of Medicine at Mount Sinai: Paolo Boffetta, MD, MPH; Jia Chen, PhD; Michael Crane, MD; William Oh, MD; Matthew Galsky, MD


Image of Emanuela  Taioli, PhD         MD
Principal Investigator: Emanuela Taioli, PhD MD
Icahn School of Medicine at Mount Sinai