Prostate Cancer Risk and Outcome in WTC Respondents


Project Number
1U01-OH010396-01A1
Institution
Icahn School of Medicine at Mount Sinai
Fiscal Year Awarded
2013
Project Duration
2 years

Description

This study represents the first in-depth analysis of prostate cancer among World Trade Center (WTC) rescue and recovery workers. The study results will have practical implications on the surveillance and clinical management of prostate cancer, which is the most common cancer among male WTC Health Program members. The study will generate novel data on biomarkers of prostate cancer aggressiveness that could be used to make decisions on clinical treatment.

Research Objectives

Abstract

An excess incidence of prostate cancer has been identified among World Trade Center (WTC) rescue and recovery workers included in the WTC Health Program (WTCHP) at Mount Sinai in New York. An excess has also been reported among WTC-exposed firefighters included in a separate program. It is unclear whether the excess is associated with WTC-related exposures or represents an artifact.

The objectives of this project are to elucidate the reasons for the increased incidence of prostate cancer among WTCHP participants and to explore the behavior of these cancers.

Contributors

Icahn School of Medicine at Mount Sinai: Paolo Boffetta, MD, MPH; Jia Chen, PhD; Michael Crane, MD; William Oh, MD; Matthew Galsky, MD

Publications

Image of Emanuela  Taioli, PhD         MD
Principal Investigator: Emanuela Taioli, PhD MD
Icahn School of Medicine at Mount Sinai
emanuela.taioli@mountsinai.org
516-465-3093