Prevention of Work-related Asthma: Study Search

Prevention LevelSecondary
AuthorAnees
Study Year2006
CountryUK
Molecular Weight of AgentBoth
Agent CategoryVarious
Specific AgentFlour, latex, wood dust, isocyanates, metal, biocidal agents, colophony, oil mists
Occupation Not specified
Outcome/DiagnosisFEV1 decline in occupational asthma
Activity Intervention Removal from exposure (at least 1 year)
Participation RateLimitation: no report of participation rate 156 subjects with occupational asthma.
Intervention EffectivenessOnly 90 subjects had FEV1 measurements for at least 1 year before removal from exposure (median 2.9 years). The mean (SE) rate of decline of these 90 subjects was 100.9 (17.7) ml/year. 114 subjects had FEV1 measurements for 1 year after removal from exposure, and their FEV1 had improved by a mean (SE) of 12.3(31.6) ml. 86 subjects had FEV1 measurements greater than 1 year (median 2.6 years, interquartile range (IQR) 1.7-4.6) after removal from exposure. The mean (SE) rate of FEV1 decline starting at 6 months after removal from exposure was 26.6 (18.0) ml/year for this group. The decline was not significantly worse in current smokers than in never smokers.
Page last reviewed: February 20, 2020