Prevention of Work-related Asthma: Study Search

Prevention LevelSecondary
AuthorPisati G
Study Year2007
CountryItaly
Molecular Weight of AgentLMW
Agent CategoryDiisocyanates
Specific AgentToluene diisocyanate (TDI)
Occupation Not specified
Outcome/DiagnosisOccupational asthma
Activity Intervention Removal from exposure to TDI (average: 58 Months)
Participation Rate25 of 44 (57%) subjects with TDI-induced occupational asthma
Intervention Effectiveness1. Seven subjects had a positive response to inhaled TDI, and they complained of respiratory symptoms and needed medication. Their symptom score, medication score and PD20 were unchanged since diagnosis. 2. Eighteen patients had no response to TDI. a. 8 of 18 still had asthmatic symptoms, but with significantly improved symptom and medication scores since diagnosis. b. 10 of 18 had no symptoms and medication in past 12 months, and were no longer asthmatic.
Page last reviewed: February 20, 2020