Prevention of Work-related Asthma: Study Search

Prevention LevelPrimary
Study Year1993
Molecular Weight of AgentLMW
Agent CategoryDiisocyanates
Specific AgentDiphenylmethane diisocyanate (MDI)
Occupation Workers in a urethane mold plant
Outcome/DiagnosisOccupational asthma
Activity Intervention Plant design leading to reduction of exposure to MDI
Participation Rate243 of 243 eligible subjects (Participation rate: 100%)
Intervention EffectivenessStrict control and monitoring of ambient MDI exposure was associated with low prevalence of OA (3 of 243 subjects, 1.2%), which is less than the prevalence of 5% estimated in another plant with workers exposed to MDI.
Page last reviewed: February 20, 2020