Prevention of Work-related Asthma: Study Search

Prevention LevelSecondary
Study Year1998
Molecular Weight of AgentHMW
Agent CategoryAnimal-derived antigens
Specific AgentLaboratory animal allergen
Occupation Laboratory animal handlers (Includes cohort reported by Willers, 1992)
Outcome/DiagnosisOccupational asthma, rhinitis
Activity Intervention Redesign of animal stables, filter top cages, installation of ventilation airflow systems, education and training, personal protective devices (7 years)
Participation Rate35 of 51 eligible subjects (Participation rate: 69%)
Intervention EffectivenessNo subjects developed additional positive skin prick test to laboratory animals. Sensitized workers at baseline were more likely to have stopped working than non-sensitized workers. Subjects sensitized to laboratory animals had a minor increase in airway responsiveness at follow-up (p=0.03).
Page last reviewed: February 20, 2020