Prevention of Work-related Asthma: Study Search

Prevention LevelSecondary
Study Year1998
Molecular Weight of AgentLMW
Agent CategoryAnhydrides
Specific AgentTetrachlorophthalic anhydride (TCPA)
Occupation Process workers using TCPA (Includes cohort reported by Venables, 1987 and Howe, 1983)
Outcome/DiagnosisOccupational asthma
Activity Intervention Removal from exposure (1980, 12 years)
Participation Rate6 of 6 eligible subjects (Participation rate: 100%)
Intervention EffectivenessFrom 1984-1992, there were no trends observed in improvement of symptoms, bronchial responsiveness, PEF variability, and in decreased use of inhaled corticosteroids, despite progressive fall of specific IgE (n=6). Limitation: no comparison group.
Page last reviewed: February 20, 2020