Prevention of Work-related Asthma: Study Search

Prevention LevelSecondary
AuthorGrammer
Study Year1993
CountryUSA
Molecular Weight of AgentLMW
Agent CategoryAnhydrides
Specific AgentTrimelletic anhydride (TMA)
Occupation Workers manufacturing TMA (Includes cohort reported by Zeiss, 1977)
Outcome/DiagnosisLate asthma, asthma-rhinitis
Activity Intervention Transfer to low exposure area (median: 8 years, late asthma; 9.5 years, asthma-rhinitis)
Participation RateLimitation: no report of participation rate
Intervention EffectivenessSeven of 12 subjects with asthma-rhinitis continued to have moderate or severe symptoms, abnormal pulmonary function, and elevated IgE. All subjects with late asthma (n=3) improved in symptoms, pulmonary function, and IgE. Limitation: no comparison group.
Page last reviewed: February 20, 2020