Prevention of Work-related Asthma: Study Search

Prevention LevelSecondary
Study Year1984
Molecular Weight of AgentLMW
Agent CategoryDiisocyanates
Specific AgentToluene diisocyanate (TDI)
Occupation Furniture manufacturing workers
Outcome/DiagnosisAsthmatic and non-asthmatic respiratory disease
Activity Intervention Removal from exposure (2 years)
Participation RateLimitation: no report of participation rate
Intervention EffectivenessEight of 12 subjects with asthma reported dyspnea, while wheezing with PFT remain unchanged. Bronchial hyperresponsiveness declined in 3 of 12 subjects. Fifteen subjects with continued exposure experienced a decline in PFT (p<0.05) with 10 of 15 subjects presenting with symptoms of chronic bronchitis.
Page last reviewed: February 20, 2020