Prevention of Work-related Asthma: Study Search

Prevention LevelPrimary
AuthorCullinan
Study Year2000
CountryUK
Molecular Weight of AgentHMW
Agent CategoryBiological enzyme
Specific AgentBacillus subtilis derived detergent enzymes (protease, amylase, cellulase)
Occupation Detergent industry workers
Outcome/DiagnosisOccupational asthma
Activity Intervention Encapsulation of enzyme, modern process techniques
Participation Rate350 of 432 eligible subjects (Participation rate: 81%)
Intervention EffectivenessEstimated total of 56 cases of occupational asthma in the current workforce is considered as high, or higher, than within the industry before encapsulation. Airborne enzyme concentration measurements (n=1767) for the most recent year prior to data collection indicate that 5% of the measurements were above industry guidelines.
Page last reviewed: February 20, 2020